IRCT201104096152N1 IRCT 2011-06-07 Kordestan University of Medical Sciences and Health Services Comparison of the effectiveness of clomiphene citrate, tamoxifen and letrozole in ovulation induction Comparison of the effectiveness of clomiphene citrate, tamoxifen and letrozole in ovulation induction in infertility due to isolated unovulation 2007-04-21 anticipated 150 Complete https://irct.ir/trial/6588 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A Infertility. Intervention 1: Group A received clomiphene 50 mg up to 150mg for 5-7days. Treatment starded with minimum dose and effect of drug monitored by sonography. Drugs have been increased in dose and duration to achieve mature follicle 18mm. If patients achived pregnancy or were not responding to treatment with maximum dose for 7days or failed to concept after six months, treatment was discontinued. Intervention 2: Group B received tamoxifen 10 mg up to 30mg for 5-7days. Treatment starded with minimum dose and effect of drug monitored by sonography. Drugs have been increased in dose and duration to achieve mature follicle 18mm. If patients achived pregnancy or were not responding to treatment with maximum dose for 7days or failed to concept after six months, treatment was discontinued. Intervention 3: Group C received letrozole 2.5 mg up to 7.5mg for 5-7days. Treatment starded with minimum dose and effect of drug monitored by sonography. Drugs have been increased in dose and duration to achieve mature follicle 18mm. If patients achived pregnanvy or were not responding to treatment with maximum dose for 7days or failed to concept after six months, treatment was discontinued.