]>
IRCT20141209020258N176 IRCT 2022-10-03 Arak University of Medical Sciences The effect of dextrose injection in preventing postoperative nausea and vomiting in patients undergoing cholecystectomylaparoscopic surgery The effect of dextrose injection in preventing postoperative nausea and vomiting in patients undergoing cholecystectomylaparoscopic surgery 2022-10-07 anticipated 100 Complete https://irct.ir/trial/65903 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients will be allocated into 2 groups using a permuted balanced block randomization method with the size of blocks 4 and 8. Random sequence will be generated by an epidemiologist by running an online program in sealed envelope website (https://www.sealedenvelope.com/). Random chain concealment is done by opaque envelope method, Blinding description: The study is double-blind. The analysis is done by the analyst and outcome evaluator (two-blind) and the participant. Analysts, evaluators and participants are not aware of the consequences of grouping. The specialist assistant is unaware of the type of operation in each group and the surgeon is aware of the type of operation and patients are not aware of their group. 2-3 Cholecystectomy laparoscopic surgery. Intervention 1: Intervention group: 10 millileter in kilogeram in hour of Ringer's lactate serum along with 500 miligram in kilogeram of 5% dextrose will be given. The solutions are infused 5 minutes before induction of anesthesia until the end of the procedure. Intervention 2: Control group: they will receive Ringer's lactate serum with 0.9% normal saline with the same volume as the intervention group. The solutions are infused 5 minutes before the induction of anesthesia until the end of the procedure. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information
public Dr Hesamedin Modir
Valiasr Hospital, Valiasr squre, Shahid Shirodi street
Arak Iran (Islamic Republic of) 3814957558 +98 86 3222 2003 modir.he@gmail.com Arak University of Medical Sciences scientific Dr Behnam Mahmodie
Valiasr Hospital, Valiasr squre, Shahid Shirodi street
Arak Iran (Islamic Republic of) 3814957558 +98 86 3222 2003 mahmodie@arakmu.ac.ir Arak University of Medical Sciences Iran (Islamic Republic of) All candidates for laparoscopic cholecystectomy Age between 30 and 70 years ASA class I and II Patients under general anesthesia The duration of surgery is between 60-150 minutes Absence of Parkinson's disease, motion sickness or history of chemotherapy Absence of diabetes 30 years 70 years Both All patients who do not undergo general anesthesia for any reason. Patients who suffer cardiac arrest during surgery. Patients whose surgery lasts more than 180 minutes. Patients who are referred to the intensive care unit for any reason. K91.86 Retained cholelithiasis following cholecystectomy Treatment - Drugs Treatment - Drugs Intervention group: 10 millileter in kilogeram in hour of Ringer's lactate serum along with 500 miligram in kilogeram of 5% dextrose will be given. The solutions are infused 5 minutes before induction of anesthesia until the end of the procedure. Control group: they will receive Ringer's lactate serum with 0.9% normal saline with the same volume as the intervention group. The solutions are infused 5 minutes before the induction of anesthesia until the end of the procedure. Vomitting. Timepoint: In recovery, 2, 4, 6, 12 and 24 hours after the operation. Method of measurement: Score from 0 to 4 (no vomiting gets zero and frequent vomiting gets 4.). Severe nausea. Timepoint: Recovery, 2, 4, 6, 12 and 24 hours after the operation. Method of measurement: VAS visual analog scale. Mean of dose of metoclopramide in 24 hours. Timepoint: At the end of the study. Method of measurement: Physical examination. Arak University of Medical Sciences Approved 2022-05-01 Ethics comittee of Arak University of Medical Sciences Ethics comittee, Research center, Payambar Azam complex, Basij squre ,Sardasht,Arak Arak Markazi Iran (Islamic Republic of)