IRCT201212166186N1 IRCT 2012-12-20 research office of anesthesiology and pain, guilan university of medical sciences Comparison of Pulsed Radiofrequency and TENS on decreasing of Diabetic neuropathy symptoms in Lower extremity Comparison of Pulsed Radiofrequency and Transcutaneous electrical nerve stimulation on decreasing of Diabetic neuropathy symptoms in Lower extremity in patients who did not respond to medications 2012-12-21 anticipated 60 Complete https://irct.ir/trial/6613 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A Diabetes mellitus. Intervention 1: for TENS group after cleaning the skin with alcohol, patch electrodes will be attached to the skin of lateral inferior part of knee and forfoot. then electrical impulses will be generated with 80 Hz and 50 mA for 20 minutes. there will be 10 sessions of TENS daily. Intervention 2: for RF group in operation room with fluoroscopic guide, the patient will be in prone position and RF needle will be inserted percutaneously from lumbar region to the lumbar sympathetic chain in anterolateral portion of L2 L3 and L4 vertebrates. the needle position will be approved by injection of omnipaque 240 and sensory and motor stimulating test.patients will receive 3 cycles of pulsed radiofrequency lasting for 180 seconds for each of the vertebrates.