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IRCT20220711055433N2 IRCT 2022-10-27 Mashhad University of Medical Sciences Comparative cefixime and levofloxacin on infections after urinary tract dilatation A comparative study on the effects of prevention antibiotics cefixime and levofloxacin on infections after urinary tract dilatation in patients with recurrent stenosis 2021-01-06 anticipated 50 Complete https://irct.ir/trial/66183 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Randomization description: The generation of random numbers using random blocks and the envelope method is such that the envelopes will be prepared by a member of the research team and random numbers with the help of random blocks, printed and placed inside the envelope. The lid of the envelopes will be closed and its contents will not be visible from the outside. Then the person takes an envelope and enters the intervention or control group based on the contents of the envelope, Blinding description: The evaluator and the analyst unaware of the intervention and control groups. 3 Urethral Stricture. Intervention 1: Intervention group: Before and after urethral dilatation, a 500mg tablet of levofloxacin is given for 3 days (one dose before urethral dilatation and two doses after urethral dilatation). Intervention 2: Control group: Before and after urethral dilatation, a tablet cefixime 400 mg is given for 3 days (one dose before urethral dilatation and two doses after urethral dilatation). No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no further information
public Amir Abbas Asadpour
Urology Department, 3rd floor, Ghaem Hospital, Ahmadabad Blvd
Mashhad Iran (Islamic Republic of) 9176699199 +98 51 3843 2256 Asadpouraa@mums.ac.ir Mashhad University of Medical Sciences scientific Amir Abbas Asadpour
Urology Department, 3rd floor, Ghaem Hospital, Ahmadabad Blvd
mashhad Iran (Islamic Republic of) 9176699199 +98 51 3843 2256 Asadpouraa@mums.ac.ir Mashhad University of Medical Sciences Iran (Islamic Republic of) Single urethral stricture and stricture length less than 2 cm Strictures shorter than 1.5 cm in the anterior urethra Age older than 18 years old 18 years no limit Male Patient refusal of participation History of allergy to levofloxacin and cefixime N35.9 Urethral stricture, unspecified Treatment - Drugs Treatment - Drugs Intervention group: Before and after urethral dilatation, a 500mg tablet of levofloxacin is given for 3 days (one dose before urethral dilatation and two doses after urethral dilatation). Control group: Before and after urethral dilatation, a tablet cefixime 400 mg is given for 3 days (one dose before urethral dilatation and two doses after urethral dilatation). Urinary tract infections after urethral dilatation. Timepoint: The rate of improvement in urinary tract infection in the first, second and third months after dilatation. Method of measurement: The use of Urine analysis and Urine culture. Side effects caused by cefixime or levofloxacin. Timepoint: 72 hours after urethral dilatation. Method of measurement: Medical records. Mashhad University of Medical Sciences Approved 2019-09-03 Ethics committee of Mashhad University of Medical Sciences Ghoreshi Building, Daneshgah St. Mashhad Razavi Khorasan Iran (Islamic Republic of)