IRCT20170828035961N2 IRCT 2023-07-01 Esfahan University of Medical Sciences Investigation of the effect of letrozole in the treatment of ectopic pregnancies compared to methotrexate. Investigating the success rate of aromatase inhibitor (letrozole) in the treatment of ectopic pregnancies compared to methotrexate. 2023-05-22 anticipated 40 Complete https://irct.ir/trial/66329 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: In this study, 40 eligible ectopic pregnant will be selected randomly. Then the letters A and B are written on 20sheets and each one is placed in an envelope. Each patient is then asked to choose one of the envelopes. Depending on the selected envelope, the patient is assigned to one of two groups, Blinding description: In this study, two drugs, letrozole and methotrexate, are placed in coded packages by the pharmacy manager and delivered to the researcher, who is unaware of the type of each. Medications are prescribed. Also, the person recording the clinical and basic information of the patients as well as the statistical analyst will not be aware of the type of intervention. 2 Ectopic pregnancy.. Intervention 1: Intervention group: In the group receiving methotrexate, a single dose of methotrexate with a dose of 50 mg per square meter of the body will be calculated and injected intramuscularly or subcutaneously. Intervention 2: Intervention group: In the group receiving letrozole, 2.5 mg tablets are prescribed twice a day for 10 consecutive days. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no further information