IRCT20221020056250N1 IRCT 2022-12-07 Gorgan University of Medical Sciences Investigating the effects of three drugs, midazolam, propofol and dexmedetomidine, on hemodynamic changes in cataract surgery patients. ندارد A comparison between the effects of midazolam, propofol, and dexmedethomidine on hemodynamics variation in patients undergoing cataract surgery under local anesthesia 2022-10-23 anticipated 110 Complete https://irct.ir/trial/66432 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: ندارد, Randomization description: In this study, a simple random allocation method will be used using a table of random numbers, so that in order to hide it, we used the double-blind method, so that neither the patient nor the researchers related to the patients were aware of the type of study group and the selection of the patient. His group and the type of medicine received will be done by one of the researchers not related to the patient (the person injecting the medicine who is an anesthesiologist), Blinding description: In this study, we have used the double-blind method that the patient and the researchers related to the study were not aware of the type of study group, patient selection, patient grouping and the type of drug received by one of the researchers not related to the patient (injector drug, which is an anesthesiologist) was done in such a way that according to the three types of injectable drugs, three types of syringes were used, and only the anesthesiologist was aware of the type of contents of the syringes and the drugs received by the patients. 4 Cataract surgery. Intervention 1: The first intervention group: midazolam drug with a sedative dose of 100-25 µg/kg is injected as a intravenous bolus once before surgery for one minute. Intervention 2: The second intervention group: propofol with a low sedation dose, 25-100 µg/kg, is injected as a intravenous bolus once before surgery for one minute. Intervention 3: The third intervention group: dexmedetomidine with a low sedation dose of 0.5-1 µg/kg is injected as a intravenous bolus once before surgery for one minute. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is University does not allow publication