IRCT20140705018373N6 IRCT 2022-12-24 Tabriz University of Medical Sciences Effects and complications of classic and nanofat fat injections in reducing wrinkles Effects and complications of classic and nanofat fat injections in reducing wrinkles, dimples and dark circles around the eyes 2022-12-22 anticipated 40 Complete https://irct.ir/trial/67049 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization was done using patient file numbers and using even or odd numbers. The criterion is the last digit of the number and the number zero will be considered even. Even numbers will be considered as intervention group and odd numbers as control group, Blinding description: The dermatologist evaluating the final effect of the intervention and possible complications as well as the person analyzing the data will be blinded to the type of intervention. 3 Condition 1: Wrinkles around the eyes. Condition 2: Dimples around the eyes. Condition 3: Dark circles under the eyes. Intervention 1: Intervention group: 20 cc of fat will be injected, 10 to 15 cc in the form of micrograft (2 to 3 cc for each eye) and 4 to 5 cc in the form of nanofat (1 to 2 cc for each eye). Intervention 2: Control group: 15 cc will be injected as a micrograft (2 to 3 cc for each eye). Yes - There is a plan to make this available What will be shared: Study data is categorized and coded with no identifiable individuals. When: Access to study data after publication of the result is available in the journal. To whom: Anyone interested in using the data can access the study data. Conditions: Study data can be used for comparison with other results. Where to obtain: Refer to the study's scientific or public accountability person for data. How to obtain: The request will be sent by email to person responsible for scientific or public inquiries. Comments: