IRCT20160524028038N14 IRCT 2022-12-19 Yasouj University of Medical Sciences Lactofem and sexual function Evaluating the effect of Lactofem supplementation on sexual performance of women with depression compared to antidepressant treatment alone 2022-12-11 anticipated 104 Complete https://irct.ir/trial/67103 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization method: simple; Random unit: Individual; Randomization tool: Statistical software “computer; Hiding method: Use 104 sealed envelopes encoded and non-transparent in the package for the allocation of subjects to intervention and control groups. The research units will be divided into two clinical groups with a ratio of 1:1 using the software to receive antidepressants alone or Lactofem supplement. 3 Depression. Intervention 1: Intervention group: Selective serotonin reuptake inhibitor (SSRI) antidepressants plus one Lactofem capsule (including Lactobacillus acidophilus 109 ، 2, Bifidobacterium bifidus 109 ، 2, Lactobacillus rutri 2 × 109, Lactobacillus fermentum 109 × 2; capsule weight of 500 mg bio-capsule) made by Iranian zist-takhmir Company was administered daily for 3 months orally. Intervention 2: Control group: Taking selective serotonin reuptake inhibitor (SSRI) antidepressants such as fluoxetine, sertraline, fluvoxamine, citalopram, escitalopram, paroxetine alone. No - There is not a plan to make this available Justification or reason for not sharing IPD is No more information