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IRCT20221203056697N1 IRCT 2023-01-02 Zahedan University of Medical Sciences Comparison of pregnancy rate between two methods of tubal sperm perfusion with standard intrauterine sperm insemination Comparison of the pregnancy rate between two methods of tubal sperm perfusion with standard intrauterine sperm insemination in infertile patients referred to the infertility clinic 2019-09-21 anticipated 60 Complete https://irct.ir/trial/67177 interventional Randomization: N/A, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Health service research, Blinding description: The outcome assessor and data analyst were blinded to patient characteristics and patient grouping. N/A positive pregnancy. Intervention 1: Intervention group: On days 3-7 of the monthly cycle after the ultrasound, 2 tablets of letrozole 2.5 mg (Iran hormone. Company) are prescribed daily for 5 nights. Then HMG gonadotropin or Gonal-f (Karma Company) was prescribed from day 7 to 10 cycles based on the patient's need in the amount of 3 to 4 pills daily. Next, 5 to 7 days after the last dose of letrozole, ultrasound is performed. When the follicles reach the size of 18 to 24 mm, HCG (Karma Company) is injected intramuscularly, and 36 to 48 hours later, the semen sample prepared by the gradient process with a volume of 4-6 cc is injected into the uterus through the IUI catheter.IUI group, which is intrauterine insemination of sperm. Intervention 2: Intervention group: FSP group,which is Fallopian tube sperm perfusion. Yes - There is a plan to make this available What will be shared: Comparison of pregnancy rate between IUI and Fallopian tube Sperm Perfusion methods in patients with infertility referring to Ali ibn Abitaleb Hospital in Zahedan in 2019 When: The access period starts 6 months after the results are published To whom: Researchers working in academic and scientific institutions Conditions: Request from the responsible author of the article Where to obtain: farahnaz1826@yahoo.com How to obtain: request to farahnaz1826@yahoo.com Comments:
public Farahnaz Farzaneh
Persian Gulf Highway - University of Medical Sciences Campus Complex
Zahedan Iran (Islamic Republic of) 9816743463 +98 54 3337 2151 farahnaz1826@yahoo.com Zahedan University of Medical Sciences scientific Farahnaz Farzaneh
Hemmat steet
Tehran Iran (Islamic Republic of) 9816743463 +98 21 6650 9283 farahnaz1826@yahoo.com Zahedan University of Medical Sciences Iran (Islamic Republic of) The age of the woman is 20 to 40 years Infertility less than 10 years Body mass index (BMI) less than 27 Kg/m2 Hysterosalpingography (at least one normal tube) 20 years 40 years Female Male infertility (moderate to severe oligospermia) Bilateral obstruction in hysterosalpingography Ovaries with very poor function Very poor ovarian reserve The presence of uterine anomalies at the same time and the presence of obstruction of the uterine tubes Treatment - Other Treatment - Other Intervention group: On days 3-7 of the monthly cycle after the ultrasound, 2 tablets of letrozole 2.5 mg (Iran hormone. Company) are prescribed daily for 5 nights. Then HMG gonadotropin or Gonal-f (Karma Company) was prescribed from day 7 to 10 cycles based on the patient's need in the amount of 3 to 4 pills daily. Next, 5 to 7 days after the last dose of letrozole, ultrasound is performed. When the follicles reach the size of 18 to 24 mm, HCG (Karma Company) is injected intramuscularly, and 36 to 48 hours later, the semen sample prepared by the gradient process with a volume of 4-6 cc is injected into the uterus through the IUI catheter.IUI group, which is intrauterine insemination of sperm Intervention group: FSP group,which is Fallopian tube sperm perfusion Positive pregnancy. Timepoint: Two weeks after treatment. Method of measurement: β-Hcg test. Zahedan University of Medical Sciences Approved 2020-02-16 Ethics committee of Zahedan University of Medical Sciences Persian Gulf Highway - University of Medical Sciences Campus Complex zahedan Sistan-va-Balouchestan Iran (Islamic Republic of)