IRCT20160524028038N13 IRCT 2022-12-09 Yasouj University of Medical Sciences The effect of sildenafil and melatonin on sexual function Evaluation of the effect of sildenafil along with melatonin on the sexual function of patients with polycystic ovary syndrome treated with metformin. 2022-12-21 anticipated 216 Complete https://irct.ir/trial/67220 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The randomization method is simple. The random allocation sequence will be determined using the "computer Random generation" computer program. The sealed envelopes encoded and non-transparent (A، B ، C ، D) for the allocation of subjects to intervention (A، B ، C) and control (D) groups will be used. 3 polycystic ovarian syndrome. Intervention 1: Intervention group: Sildenafil (sildenafil citrate (Vizarcin) 25 mg daily) + metformin tablets (500 mg three times a day orally). Intervention 2: Intervention group: melatonin (3 mg of melatonin tablets daily (Razak Pharmaceutical Company, Iran) along with metformin tablets (500 mg orally three times a day). Intervention 3: Intervention group: Melatonin (3 mg melatonin tablets per day, Razak Pharmaceutical Company, Iran) along with sildenafil (25 mg sildenafil citrate (Vizarsin) per day) along with metformin tablets (500 mg orally three times a day). Intervention 4: Control group: metformin tablets (500 mg orally three times a day). No - There is not a plan to make this available Justification or reason for not sharing IPD is No more information