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IRCT20221212056786N1 IRCT 2023-07-29 Yazd University of Medical Sciences The effect of vitamin C on the repair of extracted tooth socket Investigating the effect of vitamin C on the repair of extracted tooth socket 2023-08-11 anticipated 54 Complete https://irct.ir/trial/67391 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: First, using the random allocation version 1 software under Windows, we generate a random sequence using a simple random allocation method. The result of the software is in the form of a software that specifies the numbers 1 to 54 along with the letters A, B and C, and the first qualified person will be assigned number 1, and the next people will get numbers 2 to 54. And the researcher places each qualified person in the specified group based on the random allocation table. In order to blind the random allocation, we ask the help of a third person who does not know about the interventions and the table is provided to him. When the eligible person comes, the intervention group that is with A, B and C groups will be asked by phone or SMS, and the person will be placed in the desired group, Blinding description: For the purpose of blinding, the placebo is made in the form of round tablets with a yellow coating similar to vitamin C tablets of Amin Pharmaceutical Company and poured into similar glass containers, and each batch is coded. They don't know about received and done coding. 3 The repair of extracted tooth socket. Intervention 1: Control group: placebo receiver. Intervention 2: First intervention group: Topical vitamin C receiver. Intervention 3: Second intervention group: Systemic vitamin C recipient. Yes - There is a plan to make this available What will be shared: All data can be shared When: From September 2021 to 1 year after the publication of the article To whom: For all people, including those working in academic and scientific institutions and industry Conditions: Email and call Where to obtain: mohammad arab farashahi, 09133735190, sma.farashahi_69@yahoo.com How to obtain: After sending the email, the data is transferred Comments:
public seyed mohammad arab farashahi
Faculty of Dentistry, Imam Reza Blvd., Kharat Blvd., Daheh Fajr Blvd., Yazd
Yazd Iran (Islamic Republic of) 8914881167 +98 35 3625 5881 sma.farashahi_69@yahoo.com Yazd University of Medical Sciences scientific seyed mohammad arab farashahi
Faculty of Dentistry, Imam Reza Blvd., Kharat Blvd., Daheh Fajr Blvd., Yazd
Yazd Iran (Islamic Republic of) 8914881167 +98 35 3625 5881 sma.farashahi_69@yahoo.com Yazd University of Medical Sciences Iran (Islamic Republic of) Healthy patients aged 14-40 without medical conditions (including the absence of gastrointestinal diseases such as peptic ulcer, etc.) with bilateral symmetrical non-infectious premolars who need tooth extraction for orthodontic treatment. Also have no history of smoking or alcohol consumption Women are not pregnant or breastfeeding Patients do not have psychiatric disorders Patients do not use corticosteroids, anticonvulsant drugs such as phenytoin, contraceptive drugs containing estrogen and other antioxidant supplements in the period close to the study Patients do not have history of allergy to toluidine blue The selected teeth do not have bone loss or defects 14 years 40 years Both Patients who will miss more than 1 dose of vitamin C Placebo Treatment - Drugs Treatment - Drugs Control group: placebo receiver First intervention group: Topical vitamin C receiver Second intervention group: Systemic vitamin C recipient Socket depth. Timepoint: Immediately after extraction, 7 days and 21 days after tooth extraction. Method of measurement: From the marginal gingiva to the point where the probe enters the socket in mm. Mesiodistal dimension. Timepoint: Immediately after extraction, 7 days and 21 days after tooth extraction. Method of measurement: Measurement of the mesiodistal dimension of the silent tooth at the CEJ level of the adjacent teeth in millimeters. Buccolingual dimension. Timepoint: Immediately after extraction, 7 days and 21 days after tooth extraction. Method of measurement: Measurement of the buccolingual dimension of the silent tooth at the CEJ level of the adjacent teeth in millimeters. Pharmaceutical group. Timepoint: At the beginning of the study. Method of measurement: local/systemic. Age. Timepoint: At the beginning of the study. Method of measurement: The number of years in a person's life. Sex. Timepoint: At the beginning of the study. Method of measurement: A person's physical phenotype. Yazd University of Medical Sciences Approved 2022-12-12 Research Ethics Committees of School of Dentistry-Shahid Sadoughi University of Medical Sciences Faculty of Dentistry, Imam Reza Blvd., Kharat Blvd., Daheh Fajr Blvd., Yazd yazd Yazd Iran (Islamic Republic of)