IRCT20160524028038N15 IRCT 2023-01-14 Bandare-abbas University of Medical Sciences Evaluation of the effect of sildenafil and melatonin on fertility outcomes in women with poor ovarian response Evaluation of the effect of sildenafil plus melatonin on fertility outcomes in infertile women with poor ovarian response undergoing assisted reproductive treatment. 2023-01-06 anticipated 88 Complete https://irct.ir/trial/67593 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The randomization method is simple. The random allocation sequence will be determined using the "computer Random generation" computer program. The sealed envelopes encoded and non-transparent (A، B ، C ، D) for the allocation of subjects to intervention (A، B ، C) and control (D) groups will be used. 3 Female infertility due to poor ovarian response. Intervention 1: Intervention group A: Sildenafil (sildenafil citrate 25 mg daily; Visarsin) starting from the first day of the cycle until the day of egg retrieval) along with Inofolic (Inofolic powder 4 grams daily) starting from the first day of the previous cycle for 40 days. Intervention 2: Intervention group B: Melatonin (3 mg melatonin tablets daily; Razak Pharmaceutical Company, Iran) starting from the first day of the cycle until the day of egg retrieval along with inofolic (inofolic powder 4 grams daily) starting from the first day of the previous cycle for 40 days. Intervention 3: Intervention group C: Melatonin (daily 3 mg of melatonin tablets (Razak Pharmaceutical Company, Iran), starting from the first day of the cycle until the day of egg retrieval with sildenafil (daily 25 mg of sildenafil citrate; Visarsin) starting from the first day of the cycle until the day of egg retrieval with inofolic (inofolic powder 4 grams daily) starting from the first day of the previous cycle for 40 days. Intervention 4: Control group: Inofolic (inofolic powder 4 grams daily) starting from the first day of the previous cycle for 40 days. No - There is not a plan to make this available Justification or reason for not sharing IPD is No more information