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IRCT20221226056929N1 IRCT 2022-12-29 Bandare-abbas University of Medical Sciences Investigating the effect of Gelfoam on reducing swelling, bleeding and pain after mandibular wisdom tooth surgery. Comparison between the effect of foam gel impregnated with dexamethasone and tranexamic acid on swelling, bleeding and pain after mandibular wisdom teeth surgery 2023-01-10 anticipated 58 Complete https://irct.ir/trial/67619 interventional Randomization: N/A, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Other design features: The number of 58 patients without systemic disease, not taking drugs that interfere with the tested drugs, and also the presence of mandibular wisdom teeth with a moderate degree of severity will be included in the study. Patients were divided into two groups of 29, the first group was administered dexamethasone with Gelfoam and the second group was administered tranexamic acid with Gelfoam. It is explained to the patients that they should call or refer if there is a specific problem or evidence of infection. Otherwise, the amount of pain, swelling and bleeding is measured on the first, third and sixth days, Blinding description: It is explained to the patients that they will participate in a clinical trial study and gelfoam administration is not necessary after wisdom tooth surgery according to dental reference books. All surgeries will be performed by the same surgeon using a single protocol and the same type of flap and surgical technique as well as the amount of bone removal. Then, for a series of patients, dexamethasone is used, and for the rest, tranexamic acid with Gelfoam is used, while the patient does not know its type. Then the amount of pain, swelling and bleeding is measured on the first, third and sixth days after surgery. 3 Pain, swelling and bleeding after surgery. Intervention 1: Intervention group: The use of dexamethasone-impregnated gelfoam in the socket of the mandibular wisdom tooth. Intervention 2: Intervention group: The use of Tranxamic acid-impregnated gelfoam in the socket of the mandibular wisdom tooth. Yes - There is a plan to make this available What will be shared: All data can be played after de-identifying the participants When: 6 months after recording the results To whom: Academic researchers Conditions: Systematic review articles Where to obtain: Email: neda1223roz@gmail.com Its owner: Fatme Zahmtakash How to obtain: Send email Comments:
public Dr. Hossamuddin Etemadi
Bandar Abbas Faculty of Dentistry ,Nasser Blvd
Bandar Abbas Iran (Islamic Republic of) 7914964153 +98 76 3335 0458 hessam12002@hotmail.com Bandare-abbas University of Medical Sciences scientific Dr. Hossamuddin Etemadi
Bandar Abbas Faculty of Dentistry, Nasser Blvd
Bandar Abbas Iran (Islamic Republic of) 7914964153 +98 76 3335 0458 hessam12002@hotmail.com Bandare-abbas University of Medical Sciences Iran (Islamic Republic of) All patients aged 18-60 years of both sexes and without systemic problems Patients with mandibular third molar without pericoronitis and infection People in whom it is possible to measure and track pain, swelling and bleeding. 18 years 60 years Both Patient's unwillingness to cooperate Failure to strictly follow postoperative instructions Existence of systemic diseases and pregnant women The presence of infection in the patient Patients who have unusual problems during tooth extraction Prevention Prevention Intervention group: The use of dexamethasone-impregnated gelfoam in the socket of the mandibular wisdom tooth Intervention group: The use of Tranxamic acid-impregnated gelfoam in the socket of the mandibular wisdom tooth Pain, swelling and bleeding. Timepoint: The first, third and sixth day after surgery. Method of measurement: Clinical examination and using a visual analog scale. Bandare-abbas University of Medical Sciences Approved 2022-12-24 Ethics Committee of Hormozgan University of Medical Sciences University of Medical Sciences campus, Shahrak Nabuvat, The beginning of Imam Hossein Blvd Bandar Abbas Hormozgan Iran (Islamic Republic of)