IRCT201305236318N2 IRCT 2013-06-17 Semnan University of Medical Sciences Effect of hydrogen peroxide oral rinse on incidence of Ventilator-Associated Pneumonia in hospitalized patient in critical care unit Effect of hydrogen peroxide oral rinse on incidence of Ventilator-Associated Pneumonia in hospitalized patient in critical care unit 2013-06-05 anticipated 15 Complete https://irct.ir/trial/6769 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive. N/A Ventilator-Associated Pneumonia. Intervention 1: In intervention group, after washing hands and elevation of bed's head and with wear of clear gloves, endo-tracheal tube cuff pressure reached to 25 centimeter of water and then by using of 4–6 swabs that soaked in 15 ml hydrogen peroxide solution 3% Mucous membrane of the mouth, tongue and gums is washed and then additional secretions is suctioned. Patients' mouthwashes are doing twice a day in 8 am and 4 pm for 5 days. Intervention 2: In control group, after washing hands and elevation of bed's head and with wear of clear gloves, endo-tracheal tube cuff pressure reached to 25 centimeter of water and then by using of 4–6 swabs that soaked in 15 ml saline normal 0.9% Mucous membrane of the mouth, tongue and gums is washed and then additional secretions is suctioned. Patients' mouthwashes are doing twice a day in 8 am and 4 pm for 5 days.