IRCT20221212056791N1 IRCT 2023-01-08 Tehran University of Medical Sciences Effect of Nano-emodin on palatal wound healing The effect of the photodynamic therapy with Nano-emodin on palatal wound healing after free gingival graft; a parallel clinical trial 2023-01-21 anticipated 51 Complete https://irct.ir/trial/67782 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: After graft harvesting, the patient was randomly assigned into one of the three groups of treatment using a randomization software. Random allocation, patient enrolment, and assignment was done by different clinicians. An epidemiologist who was not aware of the treatment modalities generated the random allocation sequence using a computerized block randomization process, Blinding description: To be blind, the examiners were asked to comment only on the final outcome and then their comments were recorded. Statistical analysis was done in three groups A, B and C so that the analyzer is blind to the results. A placebo gel was used in the control group to make the patient blind. 0 (exploratory trials) Evaluation of palatal wound healing after free gingival graft surgery due to lack of attached gingiva. Intervention 1: Intervention group: Placing a gel containing 10% Nano-Emodin for 5 minutes on the wound surface. Intervention 2: Intervention group: Placing a gel containing 10% Nano-Emodin for 5 minutes on the wound surface along with LED radiation for 1 minute. Intervention 3: Control group: Placing placebo gel without LED radiation. Yes - There is a plan to make this available What will be shared: Gathered data will be analyzed and then published. When: It will be determined after the article is published. To whom: Everyone (depending on the journal policies) Conditions: Published article will be public. Where to obtain: The journal that the paper is published in. How to obtain: Just sending Email to corresponding author. Comments: