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IRCT20230101057012N1 IRCT 2023-01-08 Shahid Beheshti University of Medical Sciences The effect of exercise on the mobilization of hematopoietic stem cells The effect of high-intensity interval exercise and training on the mobilization of hematopoietic stem cells in autologous bone marrow transplant patients 2023-01-10 anticipated 40 Complete https://irct.ir/trial/67808 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: Qualified subjects are selected for the research based on the file information and after obtaining informed consent. The website https://www.sealedenvelope.com is used for randomization and the generation of a random block sequence, and sealed opaque envelopes are used to hide the random allocation. Each of the generated random sequences is recorded on a card and the cards are placed in the letter envelopes in order. In order to maintain a random sequence, the outer surface of the envelopes is numbered in the same order. The lid of the letter envelopes is glued and placed in a box. The participants open one of the letter envelopes and are placed in one of the groups based on it. N/A Condition 1: Lymphoma. Condition 2: Multiple myeloma. Intervention 1: Intervention group: Performing interval exercise before apheresis. Intervention 2: Control group: Without physical activity before apheresis. Yes - There is a plan to make this available What will be shared: Data from this study and supplemental information will be available upon request after de-identifying participants' personal information. When: Data from the current study will be available immediately after publication. To whom: Data from this study and supplementary information will be available to both those working in academic and academic institutions, as well as those working in business, trade, and industry, whenever they request it. Conditions: Data from this study and supplementary information will be publicly available. However, those who wish to use them must respect copyright, not manipulate them, and cite the original study articles that will be published. Where to obtain: The raw data and supporting information for this study will be available without reservation upon request from the corresponding author. The author is Tayebe Zarekar from the Department of Biological Sciences in Sports, Faculty of Sports and Health Sciences, Shahid Beheshti University, Valenjak, Tehran, Iran. Email: t_zarekar@sbu.ac.ir. Postal code: 1983963113 How to obtain: The raw data and supporting information of this study will be available up to three weeks after their request. Comments:
public Tayebe Zarekar
Postal code: 1983969411, Shahid Shahriari square, Evin
Tehran Iran (Islamic Republic of) 1983969411 +98 21 2990 0000 t_zarekar@sbu.ac.ir Shahid Beheshti University scientific Tayebe Zarekar
Postal code: 1983969411, Shahid Shahriari square, Evin
Tehran Iran (Islamic Republic of) 1983969411 +98 21 2990 0000 t_zarekar@sbu.ac.ir Shahid Beheshti University Iran (Islamic Republic of) Lymphoma and multiple myeloma patients candidates for autologous bone marrow transplantation BMI less than 30 No history of cardiovascular disease, diabetes, autonomic disorder, kidney disease, hepatitis or lung disease Non-smoker Successful completion of exercise test up to the fourth stage Not having a movement disorder and no difficulty in exercising clinically Having a medical approval to exercise 18 years 60 years Both Inability to do exercise based on the opinion of a specialist doctor C85.1 C90.0 Unspecified B-cell lymphoma Multiple myeloma Treatment - Other Treatment - Other Intervention group: Performing interval exercise before apheresis Control group: Without physical activity before apheresis Mobilization of hematopoietic stem cells. Timepoint: Before and after exercise activity. Method of measurement: Counting hematopoietic stem cells with flow cytometry. Shahid Beheshti University of Medical Sciences Approved 2021-10-10 Ethics Committee of Shahid Beheshti University of Medical Sciences Eerabi Ave, Velenjak Tehran Tehran Iran (Islamic Republic of)