IRCT20101220005426N13 IRCT 2023-01-26 Kerman University of Medical Sciences Comparison of the effect of norepinephrine with and without dobutamine on mortality and morbidity of children with septic shock Comparison of the effect of norepinephrine with and without dobutamine on mortality and morbidity of children with septic shock admitted to the intensive care unit 2023-01-23 anticipated 40 Complete https://irct.ir/trial/67943 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: To randomize people to the two groups, the block randomization method is used in such a way that 4 blocks are used. In each block of 4, 2 people are assigned to the first group and 2 people to the second group. R statistical software is used for random block allocation, Blinding description: It is a one-sided blind method, so that the vasopressor is prescribed by the ICU specialist. Cardiac examination (cardiac indices) will be done by a pediatric cardiologist and HR-MAP and urinary tract examination will be done by the senior ICU nurse who does not know the type of vasopressor injection to the patients. Also, laboratory tests will be performed by a technician unaware of the interventions. 2 Septic shock. Intervention 1: Control group: The first group receives epinephrine at a dose of 0.1 to 1 mcg/kg in addition to common supportive treatments. Intervention 2: Intervention group: The second group, in addition to common support treatments, receive epinephrine at a dose of 0.1 to 1 mcg/kg along with 5 mcg/kg of dobutamine. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information.