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IRCT20221121056562N1 IRCT 2023-01-25 Karaj University of Medical Sciences Investigating the effect of anti-adhesion substances in reducing adhesion after laparoscopic endometriosis surgery Investigating the effect of anti-adhesion substances in reducing adhesions after laparoscopic endometriosis surgery 2023-02-19 anticipated 60 Complete https://irct.ir/trial/67974 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Randomization description: Our sample size is 60 people, with 30 people in each group. We will use the block randomization method by using: www.sealedenvelope.com. The number of blocks considered is 4, Blinding description: The statistician will be unaware of the intervention method. Participants are unaware of the type of intervention. Injections are performed by a surgeon as a result of the surgeon and assistant surgeon are aware of the type of intervention. The person who records the final result of the study is unaware of the type of intervention. 3 Endometriosis. Intervention 1: Intervention group: During laparoscopic surgery for endometriosis, after releasing the adhesions and shaving the intestine, the anti-adhesion material (interguard oxidized regenerated cellulose, 7.5-10 cm ,Samyang biofarm company, Made in Hungary) is placed placed in the parts where the adhesion is opened. Its amount is determined based on the extent of adhesion during surgery. Intervention 2: Control group: During laparoscopic endometriosis surgery, no intervention is performed. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is It is not yet known if there will be a plan to make this available
public Shiva Mahmooudzadeh
Kamali hospital; Kamali alley; Shohada square; Shahid Beheshti street
Karaj Iran (Islamic Republic of) 3149779453 +98 26 3222 2021 shiva.kani91@gmail.com Karaj University of Medical Sciences scientific Shiva Mahmooudzadeh
Kamali hospital; Kamali alley; Shohada square; Shahid Beheshti street
Karaj Iran (Islamic Republic of) 3149779453 +98 26 3222 2021 shiva.kani91@gmail.com Karaj University of Medical Sciences Iran (Islamic Republic of) Iran (Islamic Republic of) Women in the age group of 15 to 45 years Women diagnosed with infertility Women with chronic cyclic pelvic pain associated with menstruation Patients who are diagnosed with severe endometriosis (stage 3 and 4) according to clinical and ultrasound criteria. 15 years 45 years Female Pregnancy Lactating lady Laparoscopy contraindications (coagulopathy - cirrhosis - unclear anatomy - heart - lung disease) N80 Endometriosis Prevention Prevention Intervention group: During laparoscopic surgery for endometriosis, after releasing the adhesions and shaving the intestine, the anti-adhesion material (interguard oxidized regenerated cellulose, 7.5-10 cm ,Samyang biofarm company, Made in Hungary) is placed placed in the parts where the adhesion is opened. Its amount is determined based on the extent of adhesion during surgery Control group: During laparoscopic endometriosis surgery, no intervention is performed Abdominal adhesions. Timepoint: Three to six months after surgery. Method of measurement: Sonography , According to the scoring system Enzian. Karaj University of Medical Sciences Approved 2022-11-02 Ethics Committee of Alborz University of Medical Sciences Ethics committee unit; Vice Chancellor for Research; No.20; Saffarian alley; 45 Metri Golshahr street Tehran Tehran Iran (Islamic Republic of)