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IRCT20220530055028N1 IRCT 2023-01-30 Karaj University of Medical Sciences Investigating the effect of early medical treatment with enoxaparin on the rate of successful fertility following assisted reproductive methods Investigating the effect of early medical treatment with enoxaparin on the rate of successful fertility following assisted reproductive methods in comparison to assisted reproductive methods without early use of enoxaparin in Kamali Medical Education Center in 1402-1401 2023-03-11 anticipated 90 Complete https://irct.ir/trial/68255 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Our sample size is 90 people, with 45people in each group. Block randomization method was designed by epidemiologist using STATA version 13 software. Unit of randomization such is individual. The number of blocks considered is 4, Blinding description: 90 cards containing sequences of treatments will be written and a10-digit random code, as the patient’s identification number, will be provided for each packet. When the researcher announces the eligibility of a patient, the methodologist will provide the researcher with the envelope. The person evaluating the outcomes is a third person who is unaware of the random allocation process and type of treatment. Data analysis will be carried out by a statistician who is aware of all the processes performed.the participants are aware of the type of intervention. 3 Infertility. Intervention 1: Intervention group: The intervention group of patients undergoing ART at the time of embryo transfer is given subcutaneous enoxaparin at a dose of 1 mg/kg/day/sc, which continues for about two weeks later. Intervention 2: Control group: There is no intervention. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is It is not yet known if there will be a plan to make this available
public Mehrnaz Raeisidehkordi
Gohardasht
Karaj Iran (Islamic Republic of) 3149779453 +98 26 3446 0708 mraeisi283@gmail.com Karaj University of Medical Sciences scientific Mehrnaz Raeisidehkordi
Gohardasht
Karaj Iran (Islamic Republic of) 3149779453 +98 26 3446 0708 mraeisi283@gmail.com Karaj University of Medical Sciences Iran (Islamic Republic of) Age between 20-40 years BMI body mass index between 18-30 Having an egg suitable for fertilization Having a suitable endometrium with a diameter greater than 7 mm 20 years 40 years Female Not having a specific medical disease that affects the study. Not taking enoxaparin chronically before the study for any reason Not having a specific coagulation disease such as platelet deficiency History of previous abortion History of successful pregnancy N97 Female infertility Treatment - Drugs N/A Intervention group: The intervention group of patients undergoing ART at the time of embryo transfer is given subcutaneous enoxaparin at a dose of 1 mg/kg/day/sc, which continues for about two weeks later. Control group: There is no intervention. Chemical pregnancy. Timepoint: 14 days after embryo transfer. Method of measurement: Serum BhCG level. Clinical pregnancy. Timepoint: 5 weeks after transfer. Method of measurement: Sonography. Abortion. Timepoint: Before the 20th week of pregnancy. Method of measurement: Sonography. Karaj University of Medical Sciences Approved 2022-12-03 Ethics committee of Alborz University of Medical Sciences Ethics committee unit; Vice Chancellor for Research; No.20; Saffarian alley; 45 Metri Golshahr street Karaj Alborz Iran (Islamic Republic of)