]>
IRCT20220614055165N1 IRCT 2023-07-18 Ghoum University of Medical Sciences Investigation of the effect of selenium on the treatment of patients undergoing coronary artery bypass surgery with a pump - Investigating the effect of high dose of selenium on the Clinical Situation of patients undergoing coronary artery bypass surgery with a pump 2023-08-23 anticipated 70 Complete https://irct.ir/trial/68549 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: This study will be performed by a random sampling method, block allocation. In such a way that In this study, 60 patients with corona will be randomly divided into two groups. The selection of groups will be based on the fact that individuals will be assigned to groups based on block randomization. Block size 4 is considered. So we have six blocks of four, ABAB, ABBA, AABB, BAAB BBAA, and BABA. The selection of each block will also be random and will be done using dice. For example, if the number 5 comes in the dice roll, the AABB block is considered Therefore, the first two patients are assigned to treatment A, and the two patients are then assigned to treatment B. The dice will be thrown ten times to complete the allocation of patients to treatment groups. 3 Coronary Artery Bypass Graft Surgery. Intervention 1: Intervention group: One vial of 500 micrograms of selenium {BIOSYN manufacturer, made in Germany} before anesthesia induction, one vial of 500 micrograms of selenium before transfer to the cardiopulmonary bypass pump and one vial of 500 micrograms of selenium after transferring the patient to the cardiopulmonary bypass pump. Intervention 2: Control group: Control group: normal saline serum at the same time as the first group, i.e. before induction of anesthesia, before transfer to cardiopulmonary bypass pump and after transfer to cardiopulmonary bypass pump. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information
public Moahmmad Saeidi
Beheshti Hospital, Beheshti Blvd, Qom, Iran
Qom Iran (Islamic Republic of) 3719964797 +98 25 3612 2000 dr.msaeidi@hotmail.com Ghoum University of Medical Sciences scientific Mohammad Saeidi
Beheshti Hospital, Beheshti Blvd, Qom, Iran
Qom Iran (Islamic Republic of) 3719964797 +98 25 3612 2000 dr.msaeidi@hotmail.com Ghoum University of Medical Sciences Iran (Islamic Republic of) Candidate patients on-pomp with Coronary artery bypass graft surgery 15 years no limit Both Patients under Off- pomp Coronary artery bypass graft surgery T82.218D Other mechanical complication of coronary artery bypass graft, subsequent encounter Treatment - Drugs Treatment - Drugs Intervention group: One vial of 500 micrograms of selenium {BIOSYN manufacturer, made in Germany} before anesthesia induction, one vial of 500 micrograms of selenium before transfer to the cardiopulmonary bypass pump and one vial of 500 micrograms of selenium after transferring the patient to the cardiopulmonary bypass pump. Control group: Control group: normal saline serum at the same time as the first group, i.e. before induction of anesthesia, before transfer to cardiopulmonary bypass pump and after transfer to cardiopulmonary bypass pump. Clinical Situation. Timepoint: Before the start of the intervention, during the intervention. Method of measurement: questionnaire. Ghoum University of Medical Sciences Approved 2022-05-10 Ethics committee of Qom University of Medical Sciences No. 83, Shahid Lotfi Niaser Ave, Safashehr Blvd Qom Ghoum Iran (Islamic Republic of)