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IRCT20230220057461N1 IRCT 2023-03-23 Gorgan University of Medical Sciences miracle fruit effect on dysgeusia Evaluation of miracle fruit effect on dysgeusia management in patients after chemotherapy 2023-04-04 anticipated 135 Complete https://irct.ir/trial/68694 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients will be randomly divided into three groups of 45 people, using a predetermined list, and each patient will be assigned a code. The first group will receive a dose of 100 mg and the second group will receive a dose of 200 mg of miracle fruit capsules. The third group, the control group, will receive a placebo. In the Excel software, we enter 45 items A, 45 items B and 45 items C in one column. In the opposite column, we generate random numbers using the rand() command and sort from small to large based on the values ​​of the second column. One of the organizers of the project, who does not evaluate the results and knows that the letters A, B and C are related to medicine or placebo, sticks these letters on the bottles of medicine and placebo and based on the randomized list in Excel. It will be allocated to referring patients, Blinding description: The study is double-blind . The person evaluating the results of the study does not know which drug or placebo group the patient is placed in. The patient is also unaware that he is placed in the drug or placebo group. 3 parageusia. Intervention 1: Intervention group1: The first intervention group consumes a dose of 100 mg of miracle fruit capsules after each meal. Intervention 2: Intervention group 2 : The second intervention group consumes a dose of 200 mg of miracle fruit capsules after each meal. Intervention 3: Control group: Control group patients will receive a placebo 10 minutes before breakfast, lunch, and dinner (3 times a day). Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information.
public Mahtab Golizadeh
8 Sayad , Sayad shirazi Ave. , Gorgan , Iran
Gorgan Iran (Islamic Republic of) 4917964404 +98 17 3255 1069 lona884@yahoo.com Gorgan University of Medical Sciences scientific Mahtab Golizadeh
Sayad 8, Sayad Shirazi Street, Gorgan, Iran
Gorgan Iran (Islamic Republic of) 4917964404 +98 17 3255 1069 lona884@yahoo.com Gorgan University of Medical Sciences Iran (Islamic Republic of) A cancer patient with the problem of taste disturbance after chemotherapy or radiotherapy patient with survival rate more than 6 months patient over 18 years old A patient with the ability to take oral medication 18 years no limit Both R43.2 Parageusia Rehabilitation Rehabilitation Placebo Intervention group1: The first intervention group consumes a dose of 100 mg of miracle fruit capsules after each meal. Intervention group 2 : The second intervention group consumes a dose of 200 mg of miracle fruit capsules after each meal. Control group: Control group patients will receive a placebo 10 minutes before breakfast, lunch, and dinner (3 times a day). Change in taste disorder. Timepoint: The beginning of the study and 14 days later. Method of measurement: questionnaire. Change of sour taste to sweet. Timepoint: The beginning of the study and 14 days later. Method of measurement: questionnaire. Gorgan University of Medical Sciences Approved 2023-01-08 Ethics committee of Gorgan University of Medical Sciences Roya building , Mehrnegar 6 , Sayad 8 , Gorgan , Iran Gorgan Golestan Iran (Islamic Republic of)