IRCT20230125057222N1 IRCT 2023-08-19 Ardabil University of Medical Sciences Effect of Nigella sativa oil in patients with polycystic ovary syndrome The effect of sativa Nigella sativa oil on serum levels of IL-6, TNF- alpha, insulin and lipid profiles in patients with polycystic ovarian syndrome 2023-09-07 anticipated 60 Complete https://irct.ir/trial/68707 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Using envelopes (A and B) containing medicine and placebo, they will be randomly divided into two groups. Based on the calculated sample size, 30 envelopes A and 30 envelopes B are placed in a lottery container, and then the envelopes are randomly removed from the container without replacement and the created sequence will be recorded, Blinding description: In this study, double-blind will be used so that the patient and the student who provides the envelope to the patient will be blind to the content of the envelopes (intervention or placebo). 3 Polycystic ovary syndrome. Intervention 1: Intervention group:subjects receiving black seed oil. In this group, subjects will receive capsules containing black seed oil with a dose of 1000 mg per day orally for three months. Black seed oil capsules will be provided by Barij Essential Oil Company (Kashan). Intervention 2: Control group: Subjects receiving placebo capsules. In this group, subjects will receive capsules containing placebo, which are similar to capsules containing black seed oil in terms of shape, color and side ingredients, orally daily for three months. Placebo capsules will be provided from Barij Essan Company (Kashan). Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Access to patient information is confidential