IRCT20181216042006N2 IRCT 2023-04-11 Birjand University of Medical Sciences Investigating the therapeutic effect of PRP (Platelet-Rich Plasma) in ovarian function prp Investigating the therapeutic effect of PRP (Platelet-Rich Plasma) in improving ovarian function in patients with infertility 2023-02-20 anticipated 20 Complete https://irct.ir/trial/69420 interventional Randomization: Not randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment. 2 Women with poor response to ovarian stimulation. Intervention group: (Women with poor response to ovarian stimulation) The statistical population of the study will be 20 infertile women referred to Roish Birjand clinic with poor response to ovarian stimulation and IVF candidates. The results of the tests related to AMH, FSH, LH and the number of AFC of the patients will be recorded by reviewing the patients' files before the intervention. The next step is the sampling of the PRP preparation. From all participants, 20 cc of blood with citrate anticoagulant will be taken. It will be taken. Using a centrifuge at a specified speed, the plasma will be separated and transferred to sterile tubes. In the next step, a high-speed centrifuge is performed according to the instructions of the kit to separate the platelet-rich plasma.In the follicular phase and in the early periods of the menstrual cycle, PRP injection will be performed under sterile conditions and under the guidance of transvaginal ultrasound in each ovary under general anesthesia by an anesthesiologist in the operating room of Roish Clinic in a stromal manner by a gynecologist. After regaining consciousness, she will be discharged. Finally, hormonal tests of AMH, FSH, LH and sonography will be performed by a gynecologist to determine the number of AFC in the first menstrual cycle after treatment to determine the effect.. No - There is not a plan to make this available Justification or reason for not sharing IPD is Due to the privacy of patients