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IRCT20230221057473N1 IRCT 2023-04-26 Shiraz University of Medical Sciences The effect of Anahil drug on pain relief after dental implant implantation Comparison of the effect of two drugs acetaminophen codeine and Anahil in combination with acetaminophen codeine on pain relief in patients needing dental implants after implant surgery 2023-04-30 anticipated 60 Complete https://irct.ir/trial/69730 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: In order to randomize in this study, simple randomization method will be used. Randomization will be done using a sealed envelope containing a bead. If there is a white bead in the envelope, the patient will be in the intervention group, and if the envelope contains a red bead, he will be placed in the control group, Blinding description: Due to the nature of the drugs, the study will be double-blind. Considering that the intervention group receives two drugs and the control group receives only one drug, the intervention and control groups must be blind to the type of treatment. Patients receive the medicine in closed envelopes with black cover that are coded (A and B). Coding is done by one of the collaborators of the project, and the researcher who will give the drugs to the patient does not know the nature of the drug inside the envelope. 1-2 Patients needing dental implants. Intervention 1: Intervention group: taking Anahil 500 mg along with acetaminophen codeine (300 mg acetaminophen + 20 mg codeine)Salamat Parmoun Amin Pharmaceutical Company every 8 hours for three days at 30 minutes after the completion of implant surgery. Intervention 2: Control group: taking acetaminophen codeine (300 mg acetaminophen + 20 mg codeine) alone Salamat Parmoun Amin Pharmaceutical Company every 8 hours for three days at 30 minutes after the completion of implant surgery. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is confidentiality
public Sheila Shahsavaripour
Qasr al-Dasht St. – Qomabad
Shiraz Iran (Islamic Republic of) 15878-71956 +98 71 3626 3193 sheilashahsavaripour@gmail.com Shiraz University of Medical Sciences scientific Sheila Shahsavaripour
Qasr al-Dasht St. – Qomabad
Shiraz Iran (Islamic Republic of) 15878-71956 +98 71 3626 3193 sheilashahsavaripour@gmail.com Shiraz University of Medical Sciences Iran (Islamic Republic of) Patients needing implants Age above 20 years Absence of systemic disease 20 years no limit Both Patients who had taken painkillers or other drugs within 24 hours before surgery. They had a history of addiction to drugs or painkillers. Patients who were pregnant or breastfeeding, or had a known sensitivity to analgesics, nonsteroidal anti-inflammatories, or cyclooxygenase-2 inhibitors. . . Treatment - Drugs Treatment - Drugs Intervention group: taking Anahil 500 mg along with acetaminophen codeine (300 mg acetaminophen + 20 mg codeine)Salamat Parmoun Amin Pharmaceutical Company every 8 hours for three days at 30 minutes after the completion of implant surgery. Control group: taking acetaminophen codeine (300 mg acetaminophen + 20 mg codeine) alone Salamat Parmoun Amin Pharmaceutical Company every 8 hours for three days at 30 minutes after the completion of implant surgery. Pain. Timepoint: 1, 3 and 7 days after implant surgery. Method of measurement: visual analog scale (VAS). Shiraz University of Medical Sciences Approved 2023-02-04 Ethics Committee of Shiraz University of Medical Sciences Qasr al-Dasht street, Qomabad Shiraz Fars Iran (Islamic Republic of)