IRCT20220625055267N1 IRCT 2023-05-18 Mashhad University of Medical Sciences Clinical evaluation of the effectiveness of a topical product prepared from cotton in stopping bleeding from the site of leech therapy Preparation, characterization and clinical evaluation of the effectiveness of a cotton-based topical product in stopping bleeding from the leech therapy wound 2023-07-23 anticipated 20 Complete https://irct.ir/trial/70026 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization method: block Randomization Unit: Individual Randomization tool: sealed envelope How to generate random sequence: Manually The patients of two groups are named with codes A and B and the size of the blocks is selected. Number 1 (in the order of ABAB) is selected in the lottery, the first patient will receive treatment A, the second patient will receive treatment B, the third patient will receive treatment A, and the fourth patient will receive treatment B. The fifth patient will be randomly selected from one of the 4 blocks and the type of treatment will be assigned to the fifth to eighth patients according to the block. A selection number has been assigned for each of the 6 blocks and the selection method of each of the blocks will be lottery style. 3 Bleeding from the site of leech therapy. Intervention 1: Intervention group: Dressing the site of leech therapy with a topical product based on cotton. Intervention 2: Control group: Dressing the site of leech therapy with routine dressing. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information.