IRCT20230506058101N1 IRCT 2023-05-31 Arak University of Medical Sciences The effect of dexamethasone, droperidol and ginger on controlling nausea and vomiting Evaluation of the prophylactic effect of dexamethasone and droperidol in comparison with dexamethasone and ginger on nausea and vomiting in patients undergoing laparoscopic cholecystectomy 2023-06-10 anticipated 152 Complete https://irct.ir/trial/70115 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive, Randomization description: To allocate the samples, the block randomization method with blocks of size 8 will be used. In this way, by using the software to generate random numbers using the block method and the randomization sequence, it will be produced according to the required sample size for the two groups. The two letters A and B can be arranged together in a block of size 8, and then a block is randomly selected from among the blocks, and the arrangement pattern in that block will be used to allocate the participants. Then this block in The original container will be placed and another block will be selected again. All these works will be done with a software called sealed envelope, Blinding description: In order to comply with blinding, firstly, the patients do not know the type of drug received, and after informed consent, they will enter the plan without knowing the type of drug received. In the droperidol group, the same capsule as the ginger capsule is used, in which flour is placed and will be given to the patient, and in the ginger group, a syringe identical to the droperidol syringe containing distilled water will be used. In order to comply with the blinding, the drugs will be prepared in advance by the anesthesiologist (project guide) in syringes of the same shape and labels 1 and 2 will be placed on them, and then they will be given to the anesthesiologist of the project for injection. The study does not know will be placed. Also, the flour and ginger capsules are prepared in the same way under the supervision of the anesthesiologist in charge of the project (supervisor) and will be given to the patients by the intern in charge of the project who does not know about the groups, so the project will be implemented in a double-blind manner. After the surgery, the project questions will be completed by the intern responsible for the project (he is not aware of the groups). 3 cholecystitis. Intervention 1: Intervention group: In group A, 8 mg of intravenous dexamethasone and 75 μg/kg droperidol and 4 oral capsules of flour are given as a placebo instead of 4 oral ginger capsules before induction of anesthesia. Intervention 2: Intervention group: In group B, patients receive 8 mg of intravenous dexamethasone and 4 ginger capsules orally and a syringe containing distilled water as a placebo instead of a syringe containing intravenous droperidol. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information.