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IRCT20200208046418N2 IRCT 2023-05-27 Tehran Naft Hospital The effect of exercise on metastatic breast cancer patients The effect of 8 weeks of resistance training on some tumor markers, liver enzymes, quality of life and fatigue in metastatic breast cancer patients 2023-06-24 anticipated 28 Complete https://irct.ir/trial/70282 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Other design features: This research consists of two training groups (intervention) and control (without intervention), Randomization description: The method of choosing a random sample is simple. In this method, first the list of names of all the members is written, then a score or number is assigned to each of them, and the required number is selected using a table of random numbers. Because the studied population is small, the lottery method is used, that is, the names of people are written on a paper and placed inside the box, then the papers are removed one by one until the desired sample size is complete. N/A Breast Cancer. Intervention 1: Intervention group: resistance training (weight training), for 8 weeks, 3 times a week, 4 movements of the upper body and 4 movements of the lower body (based on the articles). At first, each person's 1RM is measured and the training intensity will be designed based on the person's initial power, the number of repetitions for each movement is 8 to 12 repetitions in 2 to 3 sets (all the above can be adjusted based on the person's power) all recommendations American College of Sports Medicine is considered for resistance training in breast cancer patients. Intervention 2: Control group: They do not receive any intervention. Yes - There is a plan to make this available What will be shared: All the information obtained from this research project will be published as an article. Personal information of patients will remain confidential forever. When: Time of publication of articles To whom: All those for whom the information of this research project can be useful. Conditions: The research results can be made available to all interested parties. Where to obtain: To the published articles of this research project. How to obtain: Basically, raw data is not available to anyone, the results of the project can be obtained through articles. Comments:
public Somayeh Nazari
Tabaghe 3, Boloke Bahar1, Shahrake Kosar,Mydane Hesarak
Karaj Iran (Islamic Republic of) 3197937551 +98 936 641 4003 Somayeh.95.nazari@gmail.com Razi University scientific Somayeh Nazari
Tabaghe 3, Boloke Bahar1,Shahrake Kosar,Meydane Hesarak,
Karaj Iran (Islamic Republic of) 3197937551 +98 936 641 4003 Somayeh.95.nazari@gmail.com Razi University Iran (Islamic Republic of) Metastatic breast cancer patients undergoing hormone therapy in the last year Absence of fatty liver Inactivity in the last 6 months Not having a medical prohibition to participate in sports activities Absence of fracture and the possibility of its occurrence Not having an abnormality limiting sports activity Absence of cardiovascular and skeletal-muscular risk factors Absence of uncontrolled pain More than a month has passed since chemotherapy and radiotherapy 30 years 50 years Female The presence of a fracture Alcohol and smoking Age less than 30 and more than 50 Patients who are in the treatment phase of chemotherapy or radiation therapy Male patients C50.1 Malignant neoplasm of central portion of breast N/A N/A Intervention group: resistance training (weight training), for 8 weeks, 3 times a week, 4 movements of the upper body and 4 movements of the lower body (based on the articles). At first, each person's 1RM is measured and the training intensity will be designed based on the person's initial power, the number of repetitions for each movement is 8 to 12 repetitions in 2 to 3 sets (all the above can be adjusted based on the person's power) all recommendations American College of Sports Medicine is considered for resistance training in breast cancer patients. Control group: They do not receive any intervention. Tumor markers CEA، CA15-3. Timepoint: 24 hours before the intervention and 24 hours after the last training session. Method of measurement: Taking blood samples. Liver enzymes ALT, AST and ALP. Timepoint: 24 hours before the intervention and 24 hours after the last training session. Method of measurement: Taking blood samples. Quality of life. Timepoint: 24 hours before the intervention and 24 hours after the last training session. Method of measurement: Questionnaire. Fatigue. Timepoint: 24 hours before the intervention and 24 hours after the last training session. Method of measurement: Questionnaire. Razi University of Kermanshah Tehran Naft Hospital Razi University of Kermanshah Approved 2023-05-04 Razi University Research Ethics Committee Razi University, University Street, Taq Bostan Kermanshah Kermanshah Iran (Islamic Republic of)