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IRCT20230529058327N1 IRCT 2023-08-03 Bu Ali Sina University Effect of two high intensity interval training and one moderate continuous training methods on apo B/apo A ratio and ABCA1, ABCG1 expression in CABG patients. Effect of two high intensity interval training and one moderate continuous training methods on apo B/apo A ratio and ABCA1, ABCG1 expression in CABG patients. 2022-04-21 anticipated 40 Complete https://irct.ir/trial/70415 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: Simple randomization The names of 40 CABG patients who referred to the heart hospital for the second stage of rehabilitation after the operation were written on paper and each person was randomly assigned to one of the four control groups, MIT, HIIT20 and HIIT60, Blinding description: The patient was explained the exercise program, the duration of the exercise, and how to do the activity. Also, the rehabilitation doctor, physiotherapist, nurse and psychologist were aware of the type and method of exercise, but they did not know what exercise method could have a specific effect. N/A Coronary artery bypass grafting. Intervention 1: Control group: They did not receive any special training. Intervention 2: Intervention group 1: moderate-intensity continuous training (MIT). They received continuous aerobic exercises of 60%-80% maximum aerobic powe for three sessions a week with three devices: 1. Treadmill 2. Hand ergometer 3. Foot ergometer. Intervention 3: Intervention group 2: high-intensity interval training (HIIT20 sec). Intervention 4: Intervention group 3: high-intensity interval training (HIIT60 sec). Yes - There is a plan to make this available What will be shared: TC,ABCA1, ABCG1,apoA,apoB, HDL, LDL,TG When: 2023 To whom: researchers Conditions: The average data of the groups is available. Where to obtain: Ali heidarianpour: Heidarian317@gmail.com Ali Reza Ahmadvand: Alireza.led@gmail.com How to obtain: About a month Comments:
public AliReza Ahmadvand
Mahdieh Ave., Jafari Street.
Hamedan Iran (Islamic Republic of) 6517733968 +98 81 3825 4825 alireza.led@gmail.com The University of Bu Ali Sina scientific Ali Heidarianpour
Shariati Street, Pajohesh Square, Hamedan, Iran.
Hamedan Iran (Islamic Republic of) 65178-38695 +98 81 3838 1422 Heidarian317@gmail.com Bu Ali Sina University Iran (Islamic Republic of) Coronary artery bypass grafting patient male At least two months have passed since their surgery. 45 years 65 years Male Met less than 5 Injection fraction less than 30 blood pressure Arthritis I25.1 Atherosclerotic heart disease of native coronary artery Rehabilitation Rehabilitation Rehabilitation Rehabilitation Control group: They did not receive any special training. Intervention group 1: moderate-intensity continuous training (MIT). They received continuous aerobic exercises of 60%-80% maximum aerobic powe for three sessions a week with three devices: 1. Treadmill 2. Hand ergometer 3. Foot ergometer. Intervention group 2: high-intensity interval training (HIIT20 sec). Intervention group 3: high-intensity interval training (HIIT60 sec) ATP-binding cassette transporter A1 (ABCA1). Timepoint: before the start of the first training session and 48 hours after the last training session (Week 8). Method of measurement: Blood sampling from patients. ATP-binding cassette transporter B1 (ABCG1). Timepoint: before the start of the first training session and 48 hours after the last training session (Week 8). Method of measurement: Blood sampling from patients. Apolipoprotein A-1 (apoA-1). Timepoint: before the start of the first training session and 48 hours after the last training session (Week 8). Method of measurement: Blood sampling from patients. High-density lipoprotein (HDL). Timepoint: before the start of the first training session and 48 hours after the last training session (Week 8). Method of measurement: Blood sampling from patients. Apolipoprotein B (apoB-1). Timepoint: before the start of the first training session and 48 hours after the last training session (Week 8). Method of measurement: Blood sampling from patients. Bu Ali Sina University Approved 2021-02-28 Ethics Committee of Bu Ali Sina University Mahdieh Hamedan Hamadan Iran (Islamic Republic of)