IRCT20230612058464N1 IRCT 2023-07-24 Shahre-kord University of Medical Sciences Comparison of Helicobacter pylori eradication treatment in children with chronic gastritis with non-eradication treatment of Helicobacter pylori in patients with chronic gastritis Comparison of Helicobacter pylori eradication treatment in children with chronic gastritis with non-eradication treatment of Helicobacter pylori in patients with chronic gastritis 2023-06-14 anticipated 80 Complete https://irct.ir/trial/70643 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The method of randomization will be a simple randomization, so that 2 cards with the letters A and B are placed in front of the patient's parents and they choose one. Each letter belongs to one of 2 groups, Blinding description: According to the Helicobacter pylori treatment guidelines, both treatments are approved, and at the beginning of the study, the method of treatment will be explained to the parents of the participants, and only the parents will know about the type of treatment and the child will not know about the type of treatment, so the study is a single-blind study. 3 Helicobacter positive chronic gastritis. Intervention 1: Intervention group: A group of 20 children in such a way that the first 10 days of sequential therapy with S-Omeprazole 2 mg/kg/day in two divided doses and simultaneous Helicobacter pylori antibiotic treatment, first a 5-day course of amoxicillin 50 mg/kg/day in two divided doses And then on the second 5 days, they will receive clarithromycin 15 mg/kg/day in two divided doses and metronidazole 20 mg/kg/day in two divided doses, and then they will receive omeprazole 1 mg/kg/day in a single daily dose for 50 days. Helicobacter pylori antigen in stool is checked 4-8 weeks after the eradication treatment to ensure the treatment. Intervention 2: Intervention group: Group B, 20 children only proton pump inhibitor. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information