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IRCT20230523058265N1 IRCT 2023-11-18 Yasouj University of Medical Sciences The Effect of Hydroalcoholic Extracts of Yarrow, Felty Germander, and Oak Fruit Inner Bark on the Healing of Skin Ulcers in Diabetic Patients The Effects of Hydroalcoholic Extracts from Achillea millefolium, Teucrium polium, and Oak Fruit Inner Bark (Quercus brantii) Plants on the Healing of Skin Ulcers in Diabetic Patients - A Clinical Trial 2023-10-02 anticipated 25 Complete https://irct.ir/trial/70819 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Other, Purpose: Treatment, Randomization description: Randomization codes will be generated using the RAND function in Microsoft Excel and will be used for the assignment of patients, Blinding description: Participants and statistical experts will remain blinded until the results are obtained and the statistical analyses are completed. 2 Skin wound healing in diabetic patients. Intervention 1: Intervention Group: Diabetic patients with diabetic ulcers receiving standard medications and herbal washing solution with daily consumption of a total concentration of 125 mg/ml of the extract of all three plants for three weeks. Intervention 2: Control group: Diabetic patients with diabetic ulcers receiving standard medications. Yes - There is a plan to make this available What will be shared: Information and results related to the effect of the extract on patients' wounds (anonymously) When: Beginning of the access period from 1403 To whom: Patients and specialists Conditions: They will be available for other researchers, but we need the permission from the ethics committee of the university. Where to obtain: Hassan Bardania PhD of NanoBiotechnology Cellular and Molecular Research Center, Yasuj University of Medical Sciences Yasuj, Iran Email: hbardania@gmail.com Tel: 09190854796 How to obtain: About 1 month Comments:
public Dr Hassan Bardania
Dr. Shahid Jalil St.
Yasuj Iran (Islamic Republic of) 7591994799 +98 74 3334 6078 hbardania@gmail.com Yasouj University of Medical Sciences scientific Dr Hassan Bardania
Dr. Shahid Jalil St.
Yasuj Iran (Islamic Republic of) 7591994799 +98 74 3334 6078 hbardania@gmail.com Yasouj University of Medical Sciences Iran (Islamic Republic of) Informed consent to participate in the study Wound area in the range of 0.5 to 36 cm2 Duration of infection more than 4 weeks Age 18 or older 18 years no limit Both Participation in another similar research Receipt of radiation or chemotherapy in recent times Use of local growth factors or biomedicals for ulcer treatment in the last 30 days Sensitivity to the used plants Smoking or drug use S01 Open wound of head Treatment - Drugs Treatment - Drugs Intervention Group: Diabetic patients with diabetic ulcers receiving standard medications and herbal washing solution with daily consumption of a total concentration of 125 mg/ml of the extract of all three plants for three weeks. Control group: Diabetic patients with diabetic ulcers receiving standard medications Percentage reduction in the area of diabetic ulcers. Timepoint: Up 3 weeks. Method of measurement: Ulcers will be measured in square centimeters using planimetry and photography. Wound healing rate. Timepoint: Up 3 weeks. Method of measurement: Ulcers will be measured in square centimeters using planimetry and photography. Yasouj University of Medical Sciences Approved 2023-04-19 Research ethics committees of Yasuj University of Medical Sciences Dr. Shahid Jalil St. Yasuj Kohgilouyeh-va-Boyrahmad Iran (Islamic Republic of)