IRCT20230702058640N1 IRCT 2023-07-04 Vice-Chancellery for Research Hormozgan University of Medical Sciences Rate of asynchrony in mechanically ventilated patients with synchronized intermittent mandatory ventilation versus pressure-regulated volume control on the Comparison of the effect of synchronized intermittent mandatory ventilation and pressure-regulated volume control on the rate of asynchrony in mechanically ventilated patients 2023-07-23 anticipated 100 Complete https://irct.ir/trial/71040 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Randomization description: Patients will be randomized into two groups using simple randomization with individuals as the unit of randomization and a randomization table produced by the Random Allocation software. An individual uninvolved in the study will write A or B on a card and put it in an opaque envelope. Then the associated number in the randomization table will be written on the back of the envelope. One envelope will be allocated to each patient in order of entrance to the study. Allocation concealment will be done using opaque envelopes, Blinding description: The rate of asynchrony will be recorded by an individual unaware of the mode of the ventilator based on the ventilator graph and monitor; therefore, the study will be assessor-blind. 3 Mechanical ventilation. Intervention 1: Intervention group: Synchronized intermittent mandatory ventilation with a respiratory rate of 10-15/min, tidal volume of 6 mg/kg, positive end-expiratory pressure of 5-7, pressure support of 10, and trigger sensitivity of 2-3 L. Intervention 2: Intervention group: The pressure-regulated volume control mode of the ventilator. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no further information.