IRCT20230717058817N1 IRCT 2023-07-24 Ardabil University of Medical Sciences Evaluating the effect of oral Propranolol in preventing the progression of retinopathy of prematurity Evaluating the effect of oral Propranolol in pereventing the progression of retinopathy of prematurity 2023-03-21 anticipated 66 Complete https://irct.ir/trial/71347 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Used, Assignment: Other, Purpose: Treatment, Randomization description: 66 qualified neonates will be assigned to two groups of 33 people by random block allocation method (blocks of four). in this study, the block randomization method will be used so that the numbers in all groups be equal . 1 retinopathy of prematurity. Intervention 1: The intervention group will receive oral Propranolol at a dosage of 0.5 mg per kilogram every 8 hours (24 doses) until the completion of retinal vessels or discharge. It is important to note that Propranolol may affect blood pressure, blood sugar levels, and heart rate. Intervention 2: Control group: the control group will receive an equal amount of distilled water. Both groups will undergo regular retinal examinations by a doctor following the protocol, and any changes observed during the process will be documented. No - There is not a plan to make this available Justification or reason for not sharing IPD is We will decide on this later