IRCT20161106030744N3 IRCT 2023-08-21 Gorgan University of Medical Sciences Evaluation of the effect of non-surgical periodontal treatment on disease activity in patients with ankylosing spondylitis Evaluation of the effect of non-surgical periodontal treatment on disease activity in patients with ankylosing spondylitis 2023-09-02 anticipated 96 Complete https://irct.ir/trial/71825 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Supportive, Randomization description: First, random blocks of eight containing four letters A, B, C, D (each letter is repeated twice) are generated, such as ABBDCACD. Then, among these 8 blocks, 12 blocks are randomly selected and a sequence of 96 is created, and each letter is placed in a sealed envelope, numbered from 1 to 96. These envelopes, which contain one of the letters A, B, C, D, are delivered by the rheumatologist to the qualified people. Only the generator of the random sequence of 96 knows about the contents of the envelopes. Patients go to the dental clinic with the envelopes and hand over the envelopes to the periodontist. People who have the letter A will be assigned to the first group and the letter B will be assigned to the second group and so on. N/A Periodontal disease - ankylosing spondylitis. The first group: patients with AS and PD who take non-steroidal anti-inflammatory drugs (NSAID) who will receive non-surgical periodontal intervention including SRP. The second group: patients with AS and PD who take anti-tumor necrosis factor (TNF) drugs (with or without NSAID) who will receive non-surgical periodontal intervention including SRP. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information