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IRCT20230831059309N1 IRCT 2023-10-23 Zahedan University of Medical Sciences Effect of compund antioxidant medication (Sperigen tablet) on sperm DNA Fragmentation Index in infertile men aged 20 to 40 years DFI(DNA Fragmentation Index) Effect of compund antioxidant medication (Sperigen tablet) on sperm DNA Fragmentation Index in infertile men aged 20 to 40 years of age 2023-11-01 anticipated 60 Complete https://irct.ir/trial/72791 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment. 1-2 male infertility. Intervention group:patients treated with Sperigen drug (manufactured by Arvand Pharmed Company) one oral capsule every 12 hours for three months.This medicine contains of a variety of antioxidants such as vitamin C, vitamin B group, vitamin A, zinc, iron, folic acid, selenium, niacin, biotin and.... Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information
public Narges Ghaznavi Jahromi
No. 252, Alley 2/3, Sheikhi St., South Iman Blvd
Shiraz Iran (Islamic Republic of) 7185999349 +98 71 3233 1897 n.ghaznavi@zaums.ac.ir Zahedan University of Medical Sciences scientific Faramarz Fazeli
Urology department office,Ali-Ibn Abitaleb Hospital,Khalij Fars Boulevard
Zahedan Iran (Islamic Republic of) 9816743111 +98 917 141 5395 n.ghaznavi@zaums.ac.ir Zahedan University of Medical Sciences Iran (Islamic Republic of) Infertile men with abnormal spermogram (Idiopathic) age range 20 to 40 years absence of hormonal, anatomical and congenital anomalies of the urogenital system, lack of antioxidant medication usage or drugs affecting spermogram parameters such as nitrofurantoin, corticosteroids and antineoplastic. 20 years 40 years Male Men with normal spermogram use of drugs, cigarrette and waterpipe smoking patients outside the specified age range varicocele patients with Diabete, thyroid problem or any other internal disease affectting spermogram Treatment - Drugs Intervention group:patients treated with Sperigen drug (manufactured by Arvand Pharmed Company) one oral capsule every 12 hours for three months.This medicine contains of a variety of antioxidants such as vitamin C, vitamin B group, vitamin A, zinc, iron, folic acid, selenium, niacin, biotin and... Percentage of sperm DFI , total sperm count and total motile sperm in semen analysis. Timepoint: Measurement of DNA fragmentation Index before starting and 3 months after taking the drug. Method of measurement: Sperm Chromatin Structure Assay lab test (SCSA). Zahedan University of Medical Sciences Approved 2023-06-18 Ethics committee of Zahedan University of Medical Sciences Urology department office,Ali-Ibn Abitaleb Hospital,Khalij Fars Boulevard Zahedan Sistan-va-Balouchestan Iran (Islamic Republic of)