]>
IRCT20231021059781N1 IRCT 2023-10-24 Mashhad University of Medical Sciences The Effectiveness of QEEG-Guided Neurofeedback in Patients with (OCD) The Effectiveness of Adding QEEG-Guided Neurofeedback to SSRIs in Patients with Obsessive-Compulsive Disorder (OCD) 2024-02-20 anticipated 30 Complete https://irct.ir/trial/73266 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Block randomization The block randomization method is designed to randomize subjects into groups that result in equal sample sizes. This method is used to ensure a balance in sample size across groups over time. Blocks are small and balanced with predetermined group assignments, which keeps the numbers of subjects in each group similar at all times.[1,2] The block size is determined by the researcher and should be a multiple of the number of groups (i.e., with two treatment groups, block size of either 4, 6, or 8). Blocks are best used in smaller increments as researchers can more easily control balance, Blinding description: Researchers who perform data analysis and data recording are kept blind to the data of the groups. N/A A disorder characterized by the presence of persistent and recurrent irrational thoughts (obsessions), resulting in marked anxiety and repetitive excessive behaviors (compulsions) as a way to try to decrease that anxiety.. Intervention group: 30 patients with OCD who, in addition to SSRI drug treatment (fluoxetine 40-60 mg or its equivalent from another SSRI approved for OCD treatment), are treated with neurofeedback based on brain mapping.. Yes - There is a plan to make this available What will be shared: The data is published in a general and summarized form, and personal information will not be published separately. When: The access period starts from 1403 for one year To whom: Researchers who participate in this study and participate in the data analysis process can have access to the data. Conditions: Conduct a similar study Where to obtain: Psychiatry and Behavioral Sciences Research Center, Mashhad University of Medical Sciences How to obtain: Having the proposal justified and approved by the ethics committee Comments:
public Ali Talaei
Ibn-e Sina Psychiatric Hospital, Hor Al Ameli Blvd., Bu-Ali Sq., Ferdowsi Sq., Mashhad, Iran
mashhad Iran (Islamic Republic of) 919583134 21 0051 37112540 Talaeia@mums.ac.ir Mashhad University of Medical Sciences scientific Ali Talaei
Ibn-e Sina Psychiatric Hospital, Hor Al Ameli Blvd., Bu-Ali Sq., Ferdowsi Sq., Mashhad, Iran
masshad Iran (Islamic Republic of) ٩١٩۵٨٣١٣۴ +98 51 3711 2540 Talaeia@mums.ac.ir Mashhad University of Medical Sciences Iran (Islamic Republic of) 1- Age between 18 and 40 years.2- Diagnosis of OCD based on DSM-1V criteria by a psychiatrist.3- Y-BOCS test score > 16.4- Filling the informed consent form.5- Absence of other Axis 1 disorders, for example, schizophrenia, bipolar disorder, depression, etc., mental retardation, substance abuse or psychiatric disorders due to medical problems that require treatment (considering the high association of obsessive-compulsive disorder with depression mild and moderate depression is allowed to enter the plan)6- Absence of other treatment or use of cognitive therapy. 18 years 40 years Both F42 Obsessive-compulsive disorder Rehabilitation Intervention group: 30 patients with OCD who, in addition to SSRI drug treatment (fluoxetine 40-60 mg or its equivalent from another SSRI approved for OCD treatment), are treated with neurofeedback based on brain mapping. Examining the level of obsession before and after the intervention in order to evaluate the effectiveness of the intervention using the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), examining the changes in brain waves related to the disease before and after the intervention using the Neuroguide software and every two weeks thereafter From the beginning of the intervention. Checking the improvement of cognitive functions such as maintaining attention, visual memory, working memory, attention shift and response inhibition by CANTAB software before and after the intervention and every two weeks after the intervention. Checking the level of anxiety and depression in two stages: Before and after the end of the intervention by Beck's anxiety and depression questionnaires. Timepoint: Illness before and after the intervention by and every two weeks after the start of the intervention. Method of measurement: (Y-BOCS)، NEUROGUID, CANTAB , BDI, BAI. Yale Brown Obsessive-Compulsive Scale. Timepoint: the beginning and end of the study,. Method of measurement: Yale Brown Obsessive-Compulsive Scale (Y-BOCS). Mashhad University of Medical Sciences Approved 2023-09-11 کارگروه منطقه ای اخلاق در پژوهش‏های زیست پزشکی دانشگاه علوم پزشکی مشهد Research Technology, Qurashi Building, next to Hoize Cinema, Mashhad, University St, Khorasan, Razavi Mashhad Razavi Khorasan Iran (Islamic Republic of)