IRCT20231022059804N1 IRCT 2023-10-27 Semnan University of Medical Sciences Assessment of the effect of high flow of cardiopulmonary pump on the laboratory findings and cerebral perfusion in patients undergo open heart surgery Clinical Trial of Assessment of the effect of high flow of cardiopulmonary pump on the laboratory findings and cerebral perfusion in patients undergo open heart surgery 2023-10-24 anticipated 60 Complete https://irct.ir/trial/73320 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: From the start date of the project eligible patients entered the study, these patients are randomly divided into two groups. Randomization is done using a table of random numbers. One group receives normal and standard flow and the other group receives high flow. 3 Condition 1: Open Heart Surgery using cardiopulmonary pump. Condition 2: Coronary artery bypass grafting. Intervention 1: Intervention group: High flow group: In this group of patients, a flow rate of 2.6 liters per square meter per minute is used. Intervention 2: Control group: Normal flow group: In this group, a flow rate of 2.4 liters per square meter per minute is used to establish the flow of the cardiopulmonary pump, which is the usual flow rate used during open heart surgery. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Due to the lack of similar studies and the novelty of the proposed topic, it is considered that until the samples and data analysis are completed, and also because of the wide range of variables, no decision should be made regarding the publication.