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IRCT20231017059756N1 IRCT 2023-11-06 Mashhad University of Medical Sciences Investigating the therapeutic effect of statin relative to the N-acetyl cysteine in the treatment of Helicobacter pylori patients Investigating the therapeutic effect of statin relative to the N-acetyl cysteine in the treatment of Helicobacter pylori patients 2023-10-23 anticipated 180 Complete https://irct.ir/trial/73357 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Crossover, Purpose: Treatment, Other design features: no, Randomization description: Using the site www.randomization.com, in the randomization part of the site, after selecting create a list, specify the number of groups, block sizes and the length of the list, and based on that, randomization of the list is provided, Blinding description: Sealed envelopes of medicine. 3 Helicobacter pylori patients. Intervention 1: Intervention group: receiving a 14-day regimen of Helicobacter plus statin. Intervention 2: Intervention group: receiving a 14-day regimen of Helicobacter plus n a cystein. Intervention 3: Control group: Receiving a 14-day Helicobacter regimen with placebo. Yes - There is a plan to make this available What will be shared: All data is potentially shareable after de-identifying individuals When: After the study was published To whom: all people Conditions: all people Where to obtain: The site of the University of Medical Sciences and scientific sites Through direct communication with the researcher How to obtain: There is no limit Comments: no
public javad aishy
mashhad rahaee 5 p 29
mashhad Iran (Islamic Republic of) 9177137559 +98 51 3822 6605 aishy.m5@gmail.com Mashhad University of Medical Sciences scientific javad aishy
mashhad rahaee 5 p 29
mashhad Iran (Islamic Republic of) 9177137559 +98 51 3822 6605 aishy.m5@gmail.com Mashhad University of Medical Sciences Iran (Islamic Republic of) Informed written consent Helicobacter pylori positive patients with definitive diagnosis by stool HP antigen test referring to Ghaem Hospital Age category 18 years and above 18 years no limit Both Canceling the continuation of the plan pregnancy breastfeeding Weight loss of more than 5% over the past six months Dysphagia and positive personal or family history of gastrointestinal malignancy Receiving statin and NAC during the last 6 months Having a history of gastric surgery Receiving PPI and antibiotics in the past month The presence of known drug sensitivity to any of the drugs used Known liver problems The presence of obvious gastrointestinal bleeding Occurrence of possible drug side effects due to drug intervention and possible myopathy due to statin use Other Other Other Intervention group: receiving a 14-day regimen of Helicobacter plus statin Intervention group: receiving a 14-day regimen of Helicobacter plus n a cystein Control group: Receiving a 14-day Helicobacter regimen with placebo Helicobacter pylori infection recovery rate. Timepoint: Before starting treatment and one month after starting treatment. Method of measurement: Based on Helicobacter pylori antigen test in stool exam. Mashhad University of Medical Sciences Approved 2023-10-14 Mashhad University of Medical Sciences Mashhad University of Medical Sciences mashhad Razavi Khorasan Iran (Islamic Republic of)