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IRCT20231026059863N1 IRCT 2023-10-31 The First People's Hospital effect of Ultrasound-Guided Internal Heat Acupuncture for Alleviating Posterior Lumbar Nerve Pain and Modulating Serum IL1-β, TNF-α, and PGE2 Levels. Effectiveness of Ultrasound-Guided Internal Heat Acupuncture for Alleviating Posterior Lumbar Nerve Pain and Modulating Serum IL1-β, TNF-α, and PGE2 Levels. 2023-10-15 anticipated 30 Complete https://irct.ir/trial/73432 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Participants who fulfilled the inclusion criteria were selected convenient sampling technique and were then allocated randomly to Group A and Group B using lottery method. This distribution process is hidden between participants and researchers. This was done by a research assistant who did not participate in any further research, Blinding description: This study was double-blinded. The outcome assessor who was blinded to the therapy group was recruited to take readings at pre-treatment and post-treatment values. And the patients were also blinded as they didn’t know they all have the same disorder and different techniques had been given to these patients. 1 Posterior Lumbar Nerve Pain. Intervention 1: Intervention group: 1. Ultrasound-guided internal heat acupuncture Group: Patients in the UGIHA group received acupuncture sessions twice a week for four weeks. A 0.3 mm × 40 mm disposable needle (DongBang Acupuncture Inc., Korea) was percutaneously inserted and advanced to a depth of 15-25 mm into the intervertebral foramen under real-time ultrasound guidance. The needle was then electronically activated to produce heat. Acupuncture points targeted specific regions of discomfort or dysfunction. Intervention 2: Control group: Participants in the control group received non-therapeutic ultrasound therapy sessions twice a week for four weeks. The ultrasound therapy was administered without the application of heat and did not involve needle insertion. Yes - There is a plan to make this available What will be shared: Effectiveness of Ultrasound-Guided Internal Heat Acupuncture for Alleviating Posterior Lumbar Nerve Pain and Modulating Serum IL1-β, TNF-α, and PGE2 Levels. When: When the trial has been completed after the end November 2023.The data will be available for the future use and after the completion of the trial when it get published approximately after the 4 weeks in the end of the November 2023.The summary will be available after the article get published To whom: It will be available to all teaching institue and hospital for the better cure of the patient and more over it will be avilable for the researcher as wel Conditions: Only for the research and for the benefits of the public Where to obtain: Daojing Su Orthopedic Rehabilitation(1 Ward) of Shiyan Taihe Hospital affiliated to Hubei University of Medicine 32 renmin south road,maojian district,shiyan city,hubei province 605278189@qq.com How to obtain: By application sent to 605278189@qq.com Comments:
public Daojing Su
Wudang Mountain Branch, Shiyan City,Hubei Province
Shiyan China 442000 +86 150 0273 5690 605278189@qq.com Taihe Hospital affiliated to Hubei University of Medicine scientific Zengfeng Chen
Wudang Mountain Branch, Shiyan City,Hubei Province
Shiyan China 442000 +86 150 0273 5690 284133170@qq.com First People's Hospital of Jiangxia District, Wuhan/Concorde Jiangnan Hospital China Patients aged between 18-65 years diagnosed with PLNP and reporting a pain level of at least 4 on a 10-point visual analog scale (VAS) were eligible for the study. 18 years 65 years Both Exclusion criteria included pregnancy, current use of anti-inflammatory medications, history of spinal surgery, and contraindications to acupuncture M54. 16 Posterior Lumbar Nerve Pain Treatment - Other Treatment - Other Intervention group: 1. Ultrasound-guided internal heat acupuncture Group: Patients in the UGIHA group received acupuncture sessions twice a week for four weeks. A 0.3 mm × 40 mm disposable needle (DongBang Acupuncture Inc., Korea) was percutaneously inserted and advanced to a depth of 15-25 mm into the intervertebral foramen under real-time ultrasound guidance. The needle was then electronically activated to produce heat. Acupuncture points targeted specific regions of discomfort or dysfunction Control group: Participants in the control group received non-therapeutic ultrasound therapy sessions twice a week for four weeks. The ultrasound therapy was administered without the application of heat and did not involve needle insertion. 1. Primary Outcome: Pain severity was assessed using a 10-point visual analog scale (VAS) at baseline, after the 4-week intervention period, and during follow-up visits. Timepoint: 4 weeks. Method of measurement: 1. Primary Outcome: Pain severity was assessed using a 10-point visual analog scale (VAS). Secondary Outcomes: Serum levels of IL1β, TNF-α, and PGE2 were measured before and after the treatment period using established biochemical assays. Timepoint: 4 weeks. Method of measurement: Secondary Outcomes: Serum levels of IL1β, TNF-α, and PGE2 were measured before and after the treatment period using established biochemical assays. No Approved 2023-10-01 Ethical Committee of the First People's Hospital Zhifang Culture Avenue, Jiangxia Distric Wuhan City Wuhan Hubei China