IRCT20220514054846N1 IRCT 2024-02-26 Iran University of Medical Sciences Oral melatonin effect on pain after percutaneous lumbar disc decompression: a double-blind randomized clinical trial PLDD Oral melatonin Effect on pain after percutaneous lumbar disc decompression 2023-05-28 anticipated 70 Complete https://irct.ir/trial/73471 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: It was done as Random Allocation Block by (Random Allocation Software 2.0) in groups of 10 people, Blinding description: Patients qrouping will not record in the file, so the physition who perform the procedure and whom examine in the clinic will not aware of the patients qrouping also they are not involve in the study. N/A Oral Melatonin effect on pain and disability after percutaneous disc decompression. Intervention 1: Intervention group: patients in trial group, will take 3 mg melatonin tablets in addition to drugs belong to control group. The drugs will register electronically and Medicines are prepared from the Rasool Aakram Hospital pharmacy. The patient does not pay the cost of the melatonin drug and the cost is paid to the pharmacy by researcher separatly . In this way, the drug producing company is same in all patients. Intervention 2: Control group:After PLDD patients will receive Diclofenac,pregsbaline and vitamin B1by electronic prescription.Drugs will be taken from Rasool Aakram Hospital pharmacy and drugs brand and company are the same in all patients. Yes - There is a plan to make this available What will be shared: Participants data can be shared When: starting one year after complete of study To whom: ِData will be shared for academic institutions. Conditions: The reason of needding data must be determine with detail. Where to obtain: fatemehmorssali@yahoo.com How to obtain: Up to one month after request they can receive data. Comments: