]>
IRCT20231121060132N1 IRCT 2024-01-16 Kermanshah University of Medical Sciences The effect of famotidine on reducing the side effects of prostate cancer radiotherapy Investigating the effectiveness of famotidine as a radioprotector in reducing the mucosal and hematological complications of prostate cancer radiotherapy 2023-11-26 anticipated 50 Complete https://irct.ir/trial/73869 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Randomization description: Random assignment to intervention and control groups, block randomization using blocks of size four in which two people will be in the intervention group and two people in the control group. Possible quadruple blocks will be randomly selected until the final sample size is reached. 3 Prostate cancer. Intervention 1: The control group does not receive any drug. Intervention 2: Intervention group: Famotidine tablets, 40 mg, daily, 4 hours and 3 hours before radiation therapy. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Still undecided - no release schedule yet
public Iman Fallah
Golha blvd
Kermanshah Iran (Islamic Republic of) 6714415333 +98 11 3456 9701 Imen691020@gmail.com Kermanshah University of Medical Sciences scientific Maliheh Dayani
Imam Reza Kermanshah Hospital; Parastar Blvd
Kermanshah Iran (Islamic Republic of) 6714415333 083342233766 www.d.maliheh@gmail.com Kermanshah University of Medical Sciences Iran (Islamic Republic of) Patients aged 30 to 75 with prostate cancer candidates for radiotherapy Do not receive PPI drugs and other H2 antagonist drugs 30 years 75 years Male Lack of consent to participate in the study Patients with kidney disease that cannot be prescribed famotidine C61 Malignant neoplasm of prostate Prevention Prevention The control group does not receive any drug Intervention group: Famotidine tablets, 40 mg, daily, 4 hours and 3 hours before radiation therapy Mucosal lesions. Timepoint: weekly. Method of measurement: Using the Visual Analogue Scale questionnaire. Lymphocytopenia. Timepoint: weekly. Method of measurement: Blood cell count test. Granulocytopenia. Timepoint: weekly. Method of measurement: Blood cell count test. Thrombocytopenia. Timepoint: weekly. Method of measurement: Blood cell count test. Anemia. Timepoint: weekly. Method of measurement: Blood cell count test. Kermanshah University of Medical Sciences Approved 2023-11-21 Ethics Committee of Kermanshah University of Medical Sciences Imam Reza Hospital; Parastar Blvd Kermanshah Kermanshah Iran (Islamic Republic of)