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IRCT20131112015390N8 IRCT 2024-01-06 Oroumia University of Medical Sciences The effect of skin grafts on the platelet level of burn patients Evaluation of the effect of skin grafts on the platelet level of patients after surgery in Imam Khomeini Hospital of Urmia in the first 6 months of 2019 2021-01-01 anticipated 220 Complete https://irct.ir/trial/74084 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment. N/A Burn. In patients with relatively deep or deep burns that penetrate the reticular dermis layer, blood vessels, and skin appendages, surgical debridement, and skin graft were performed to repair the burn site. For this purpose, excision and skin graft were performed in one session after the patient's initial resuscitation. In this surgical procedure, the ischemic and necrotic burnt tissue was removed layer by layer by a dermatome. Until the wound bed began to bleed, which indicated that there was blood supply from this layer and that it was not involved in a burn. After the hemostasis of bleeding, skin grafts were taken from healthy body parts that had not suffered burns. The skin grafts were taken around the thighs, and in case of the thigh's involvement, the grafts were taken from the legs, arms, forearms, and trunk. The depth of the skin removal was adjusted on the Dermatome, based on the patient’s’ need; the skin was removed on the required area, which was debrided, placed, and sutured with a stapler. At the end of the operation, the grafted area was dressed with sterile vaseline gases, and it was not opened for five days to one week. The skin that was left in place guaranteed the graft's success. The place that suffered a deep burn was repaired by replacing the person's healthy skin (autograft).. Yes - There is a plan to make this available What will be shared: All data is potentially shareable after de-identifying individuals When: Six months after the results are published To whom: All researchers who need data. Conditions: All researchers who use the data for research can apply. Where to obtain: The data will be accessible via the following email. jafarkazemzade48@gmail.com How to obtain: The ethics code of the current study will be sufficient for data delivery. Comments:
public Jafar Kazemzadeh
Ayat Allah Madras Blvd., Ershad Blvd., Imam Khomeini Teaching Hospital, Urmia
Urmia Iran (Islamic Republic of) 81351-57157 +98 44 3345 9538 jafarkazemzade48@gmail.com Oroumia University of Medical Sciences scientific Jafar Kazemzadeh
Ayat Allah Madras Blvd., Ershad Blvd., Imam Khomeini Teaching Hospital, Urmia
Urmia Iran (Islamic Republic of) 81351-57157 +98 44 3345 9538 jafarkazemzade48@gmail.com Oroumia University of Medical Sciences Iran (Islamic Republic of) Burn patients who needed skin graft surgery. Patients who were willing to participate in the study. Parents who consented to the participation of their minor patient. no limit no limit Both Patients who had no history of smoking. Patients who had no history of diabetes. Patients who did not have skin infections. Patients who did not use drugs affecting platelet factors. Treatment - Surgery In patients with relatively deep or deep burns that penetrate the reticular dermis layer, blood vessels, and skin appendages, surgical debridement, and skin graft were performed to repair the burn site. For this purpose, excision and skin graft were performed in one session after the patient's initial resuscitation. In this surgical procedure, the ischemic and necrotic burnt tissue was removed layer by layer by a dermatome. Until the wound bed began to bleed, which indicated that there was blood supply from this layer and that it was not involved in a burn. After the hemostasis of bleeding, skin grafts were taken from healthy body parts that had not suffered burns. The skin grafts were taken around the thighs, and in case of the thigh's involvement, the grafts were taken from the legs, arms, forearms, and trunk. The depth of the skin removal was adjusted on the Dermatome, based on the patient’s’ need; the skin was removed on the required area, which was debrided, placed, and sutured with a stapler. At the end of the operation, the grafted area was dressed with sterile vaseline gases, and it was not opened for five days to one week. The skin that was left in place guaranteed the graft's success. The place that suffered a deep burn was repaired by replacing the person's healthy skin (autograft). The mean platelet counts. Timepoint: Blood samples were taken from patients during surgery and on the third and fifth days after transplantation to determine the patient's platelet count (Primary outcome). Method of measurement: Sysmex KX-21N Hematology Analyzer. Oroumia University of Medical Sciences Approved 2020-11-22 Urmia University of Medical Sciences ethics committee Emergency alley, Resalat Blvd., Urmia Urmia West Azarbaijan Iran (Islamic Republic of)