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IRCT20230704058674N1 IRCT 2023-12-21 Arak University of Medical Sciences Investigating the effect of chicory in the treatment of thalassemia Evaluation the effect of Chicory in decreasing serum Ferritin and liver enzymes in major Thalassemia patients 2024-01-21 anticipated 52 Complete https://irct.ir/trial/74117 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: After the identification of the patient and his permission, he is officially included in the study. The researcher has used the random bock method. In this way, patients with two treatment models c= consumption of chicory sweat p = not consuming chicory And he used the table of random numbers with 6 transformations using the https://www.sealedenvelope.com site. The numbers 1 2 3 are specific to treatment c and 4 5 6 are specific to treatment p. Zero is also ignored. For example, using the table of six random transformations: 5 1 4 3 2 6 pccpcp, Blinding description: This study is single-blind. In this way, the researcher and the patient know about the received treatment and there is no possibility of blinding them, but to avoid bias in the analysis, the analyst will not know about the codes of the treatment group to which the patients belong. 3 Beta Thalassemia major. Intervention 1: Intervention group: Chicory herbal extract prepared from Tehran School of Traditional Medicine with a concentration of 417 mg per cc, 5 cc every 12 hours for 3 months. Intervention 2: Control group: Not consuming Chicory. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no more information
public mozhgan jafari
Rahahan street,Nurse Square,Amirkabir Hospital
Arak Iran (Islamic Republic of) 3818989489 +98 86 3403 5290 mozhgaanjafari1994@gmail.com Arak University of Medical Sciences scientific Mozhgan jafari
Rahahan street,Nurse square,Amirkabir Hospital
Arak Iran (Islamic Republic of) 3818989489 +98 86 3403 5290 mozhgaanjafari1994@gmail.com Arak University of Medical Sciences Iran (Islamic Republic of) Consent of patients to participate in the study thalassemia major patients treated with periodic pack cell transfusion ferritin>500 no limit no limit Both disinclination to participate or continue studying Occurrence of skin complications or other symptoms suggestive of sensitivity to chicory plant extract Viral hepatitis or known liver disease D56.1 Beta thalassemia Treatment - Drugs Treatment - Drugs Intervention group: Chicory herbal extract prepared from Tehran School of Traditional Medicine with a concentration of 417 mg per cc, 5 cc every 12 hours for 3 months. Control group: Not consuming Chicory Ferritin. Timepoint: Initial ferritin measurement (before the start of the intervention), 3 months after consumption of chicory. Method of measurement: Biochemistry blood test. Liver enzyme. Timepoint: Liver enzyme measurement at the beginning of the study (before consuming chicory) and three months after consuming chicory. Method of measurement: Biochemistry blood test. Medical science of Arak university Approved 2023-06-20 ethics committee of arak university of medical science forth floor,mehr3 bulding, no 5 negin ave, hepco street, arak town arak Markazi Iran (Islamic Republic of)