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IRCT20150706023081N3 IRCT 2024-03-04 Esfahan University of Medical Sciences The effect of Timolol cream in the treatment of eczema Comparison of the effect of triamcinolone 0.1% topical cream with Timolol 0.5% topical cream in the treatment of patients with hand or foot eczema 2024-03-25 anticipated 32 Complete https://irct.ir/trial/74707 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Using sealed envelope technique, patients will be randomly divided into 2 groups of 32 patients treated with triamcinolone in the right hand or foot and timolol in the left hand or foot in one group and treated with triamcinolone in the left hand or foot and timolol in the right hand or foot in the other group. There will be 32 envelopes, 16 of which will the letter "a" been written on them and the other 16 have the letter "b" written on them. For each patient who enters the study, we will randomly pick one of the envelopes and the patient will be placed in that group. The kind of treatment in group a and group b will be determined by the pharmacist so that the researcher won't be aware of the treatment for each group, Blinding description: One group applies triamcinolone cream to the right hand or foot and timolol cream to the left hand or foot, while the other group applies triamcinolone cream to the left hand or foot and timolol cream to the right hand or foot. The doctor and the patient are unaware of this, and it is the responsibility of the pharmacist to determine which group is group one and which group is group two.Both topical cream models have similar packaging. 3 eczema. Intervention 1: Intervention group 1:Triamcinolone cream 0.1% is applied to the right hand or foot once a day for 4 weeks and timolol 0.5% cream is applied to the left hand or foot once a day for 4 weeks. Intervention 2: Intervention group 2:Triamcinolone cream 0.1% is applied to the left hand or foot once a day for 4 weeks and timolol 0.5% cream is applied to the right hand or foot once a day for 4 weeks. Yes - There is a plan to make this available What will be shared: All data and variables are published except for patients' private information. When: Immediately after the article is published To whom: Professors and faculty members Conditions: To better understand the article Where to obtain: By emailing the corresponder author directly How to obtain: After sending an email to the responsible writer and confirming the identity, it will be sent. Comments:
public Fariba Iraji
Hezarjarib street
Isfahan Iran (Islamic Republic of) 8174673461 +98 31 3620 2020 iraji@med.mui.ac.ir Esfahan University of Medical Sciences scientific Fariba Iraji
Hezarjarib street
Isfahan Iran (Islamic Republic of) 8174673461 +98 31 3620 2020 iraji@med.mui.ac.ir Esfahan University of Medical Sciences Iran (Islamic Republic of) Iran (Islamic Republic of) Patients referred to Alzahra and Sediqah Tahereh skin clinic Presence of hand or foot eczema complication no limit no limit Both Cardiac arrhythmia disorders Hypertension History of syncope Pregnancy Breastfeeding L20.9 Atopic dermatitis, unspecified Treatment - Drugs Treatment - Drugs Intervention group 1:Triamcinolone cream 0.1% is applied to the right hand or foot once a day for 4 weeks and timolol 0.5% cream is applied to the left hand or foot once a day for 4 weeks. Intervention group 2:Triamcinolone cream 0.1% is applied to the left hand or foot once a day for 4 weeks and timolol 0.5% cream is applied to the right hand or foot once a day for 4 weeks. Modified Total Lesion Symptom Score( mTLSS). Timepoint: At the beginning of the study and 4 weeks and 8 weeks after the start of treatment. Method of measurement: Taking pictures and measuring the modified Total Lesion Symptom Score. Esfahan University of Medical Sciences Approved 2023-12-24 Isfahan university of medical sciences Hezarjerib Isfahan Isfehan Iran (Islamic Republic of)