IRCT20230626058586N2 IRCT 2024-01-03 Shahid Beheshti University of Medical Sciences Investigating the analgesic effects of rovacaine compounds in ACL surgery Comparison of the analgesic effects of intra-articular injection of Ropivacaine7.5% with dexmedetomidine and Ropivacaine7.5% with magnesium and Ropivacaine7.5% with ketamine after ACL surgery 2024-01-21 anticipated 60 Complete https://irct.ir/trial/74740 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Randomization description: The website www.Randomization.com was used for randomization (online randomization). For this purpose, a simple randomization model was used. The randomization unit was individual and on this website, after specifying the number of intervention groups, which were three groups, and the required number in each of these groups, the website provided us with a random table of repetitions that represented the patient number. To hide the random allocation, central randomization was used. In this method, a random sequence is placed in the possession of an individual or a specific center, and sampling is done in one or more centers at the same time. Based on the order in which the participants entered the study, the researcher contacted the relevant center and asked about the random assignment of the participants to a special group, Blinding description: This study was double-blind and the patients and evaluators were unaware of the type of treatment. Also, the study data analyst only had the codes of the treatment groups (1, 2, and 3) and they were not able to distinguish the treatment groups. 2 Pain after ACL surgery. Intervention 1: Intervention group: Intervention group: intra-articular injection of ropivacaine 7.5% with dexmedetomidine (100 micrograms in 10 ml of normal saline). Manufacturer of Rupivacaine: Sina Pishgam Darou nowin. Manufacturer of dexmedetomidine: Exir. Intervention 2: Intervention group: Intervention group: intervention group: intra-articular injection of ropivacaine 7.5% with magnesium (500 mg of 5% magnesium sulfate solution).Manufacturer of Rupivacaine: Sina Pishgam Darou nowin. Magnesium manufacturing company: Nasr. Intervention 3: Intervention group: Intervention group: Intervention group: intra-articular injection of 7.5% ropivacaine with ketamine (0.5 mg/kg). Manufacturer of Rupivacaine: Sina Pishgam Darou nowin. Ketamine manufacturing company: Exir. Yes - There is a plan to make this available What will be shared: All data can be shared after de-identification of individuals and coding of patients, including outcome demographics. When: The access period will start after the results are printed. To whom: The data will be available only to researchers working in academic and scientific institutions. Conditions: Email and request from the person in charge of the study. Where to obtain: Send a message to the email below. rmoshari@yahoo.com How to obtain: After the request by email, the person in charge of the study will send the data to the individual. Comments: