IRCT20231217060438N1 IRCT 2024-01-06 Applied Research Center, Deputy Behdad Police Command Comparing pain intensity and range of motion after high tibial osteotomy Comparing pain intensity and range of motion after using combination of NSAID and Acetaminophen with opioid analgesic protocol after high tibial osteotomy 2024-01-15 anticipated 30 Complete https://irct.ir/trial/74817 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The block randomization method was used in this study. The size of the blocks is considered to be six and will be selected randomly so that it is not predictable to the participants based on the blocks. First, we will receive using Random Allocation software and by determining the sample size, the number of groups, the type of randomization and is random the order of the blocks in the software output and will be shown in the software output of groups with letters A, B. Then, after selecting each patient based on the inclusion and non-inclusion criteria, the project manager will be informed and he will tell the type of intervention of that patient based on the order of inclusion of patients and compliance with the number mentioned in the randomization output. 2-3 Proximal Tibial Osteotomy. Intervention 1: Intervention group 1: Patients assigned to the first group will receive NSAID analgesic protocol (ibuprofen) and acetaminophen. In this group, they will take 3 tablets of ibuprofen (600 mg) every 8 hours, and two tablets of acetaminophen (500 mg) every 4 hours after taking the NSAID. Intervention 2: Intervention group 2:The intervention of the second group is oxycodone opioid, which will be used as a pain reliever after surgery. Oxycodone is 10.5 mg every 6 hours. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No decision has been made yet.