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IRCT20240109060656N1 IRCT 2024-02-08 Shiraz University of Medical Sciences herbal medicine myrrh , sesamum indicum and oral contraceptive pill for treatment of incomplete abortion comparison between herbal medicine myrrh , sesamum indicum and oral contraceptive pills for treatment of incomplete abortion 2024-01-21 anticipated 160 Complete https://irct.ir/trial/74925 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: This study includes 160 patients in 4 groups. 160 patients were divided into 40 blocks of 4. Each block is numbered and will be used for 4 patients, that is, if block number 2 is selected in the lottery, the first patient will receive treatment A, the second patient will receive treatment B, the third patient will receive treatment C, and the fourth patient will receive treatment D. The fifth patient will be randomly selected from one of the blocks and the type of treatment will be assigned to the fifth to eighth patients according to the block, Blinding description: The study was conducted in a double-blind manner, and the patients and the examiner of the results (our expert radiologist) will not be aware of the type of drug used. Each drug is placed in a box in the package with a corresponding number label so that the patient does not have any information about the type of drug used. The shape and packaging of myrrh and OCP capsules and sesame and placebo are similar. In this study, our nurse colleague in the hospital affiliated to Shiraz University of Medical Sciences will deliver medicine and placebo to the study participants based on the random block table. 1-2 incomplete abortion. Intervention 1: Intervention group: In group A, LD, which is a type of OCP tablet that is placed inside the capsule with Avacil and is prepared as a capsule. This capsule is prescribed for 40 patients for 14 days. Intervention 2: Intervention group: Group B Myrrhs capsules to 40 patients, 500 mg BID for 14 days. Intervention 3: Intervention group: Group C (n=40),Contact capsules with dried sesame extract are given to 40 patients for 14 days (BID). Intervention 4: 40 patients will receive a placebo capsule (containing Avacil) for 14 days. Yes - There is a plan to make this available What will be shared: Data related to the study will not be published When: Data related to the study will not be published To whom: Data related to the study will not be published Conditions: Data related to the study will not be published Where to obtain: Data related to the study will not be published How to obtain: Data related to the study will not be published Comments:
public Fatemeh Rowshani
Zand Street, in front of Palestine Street, central building of Shiraz University of Medical Sciences
Shiraz Iran (Islamic Republic of) 7134814336 +98 71 3230 5410 f.rowshani@gmail.com Shiraz University of Medical Sciences scientific Fatemeh Rowshani
Zand Street, in front of Palestine Street, central building of Shiraz University of Medical Sciences
Shiraz Iran (Islamic Republic of) 7134814336 +98 71 3230 5410 f.rowshani@gmail.com Shiraz University of Medical Sciences Iran (Islamic Republic of) healthy women with a normal blood count ( hemoglobin > ۹) estimated gestational age less than ۲۰ weeks with intrauterine tissue with an anterior posterior diameter ۱۵-۵۰ mm less than ۱ month post abortion BMI ≤ ۳۰ no fever no pelvic tenderness no infection in vaginal exam Age between 18 and 35 years 18 years 35 years Female Age less than 18 and more than 35 years BMI>30 Presence of infection in vaginal examination O03. 4 Spontaneous abortion Incomplete, without complication. Treatment - Drugs Treatment - Drugs Treatment - Drugs Treatment - Drugs Intervention group: In group A, LD, which is a type of OCP tablet that is placed inside the capsule with Avacil and is prepared as a capsule. This capsule is prescribed for 40 patients for 14 days Intervention group: Group B Myrrhs capsules to 40 patients, 500 mg BID for 14 days Intervention group: Group C (n=40),Contact capsules with dried sesame extract are given to 40 patients for 14 days (BID). 40 patients will receive a placebo capsule (containing Avacil) for 14 days. Remaining remnants of the placenta after abortion. Timepoint: After the end of 14 days of treatment. Method of measurement: Using the findings observed in transvaginal color doppler ultrasound. Shiraz University of Medical Sciences Approved 2023-12-24 Ethics Committee of Shiraz University of Medical Sciences Zand Street, in front of Palestine Street, central building of Shiraz University of Medical Sciences Shiraz Fars Iran (Islamic Republic of)