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IRCT20130311012781N6 IRCT 2024-02-16 Ahvaz University of Medical Sciences Comparing the efficacy of Ticagrelor and Clopidogrel in patients with Acute ischemic attack or Transient ischemic attack(TIA) Comparing the efficacy of Ticagrelor and Clopidogrel in patients with acute ischemic stroke or transient ischemic attack(TIA) 2024-02-04 anticipated 424 Complete https://irct.ir/trial/75162 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Randomization description: Randomization method: Simple random allocation, Individual randomization: unit, Randomization tool including Random numbers table. 2-3 Acute Ischemic Stroke. Intervention group: (Ticagrelor/Aspirin): Aspirin (a loading dose of 100-300 mg as one to three tablets of 100 mg on the first day and then 80 mg once a day) together with Ticagrelor (loading dose of 180 mg ) is prescribed as two tablets of 90 mg on day 1 and then 90 mg twice a day until day 30.. Yes - There is a plan to make this available What will be shared: The primary clinical outcome of participants will be shared by the analysis of collected data. When: 6 months after publication of results To whom: available for people who working in academic institutions Conditions: Primary clinical outcome of participants will be shared by tables and charts. Where to obtain: Davood kashipazha _ Department of Neurology of Golestan Hospital in Ahvaz. Email: dakashi47@gmail.com How to obtain: Please your request will be send by email. our response will be send you by email during a month. Comments:
public Maryam Alwanian
Ahvaz, Golestan region, Farvardin Street, Golestan Hospital, Department of Neurology
Ahvaz Iran (Islamic Republic of) 6441945781 +98 61 3320 4531 dr.maryamalwanian@gmail.com Ahvaz University of Medical Sciences scientific Maryam Alwanian
Ahvaz, Golestan region, Farvardin Street, Golestan Hospital, Department of Neurology
Ahvaz Iran (Islamic Republic of) 6441945781 +98 61 3320 4531 dr.maryamalwanian@gmail.com Ahvaz University of Medical Sciences Iran (Islamic Republic of) Diagnosing Ischemic Stroke or TIA based on history and neurological examination and Imaging findings by a Specialist no limit no limit Both More than 24 hours have passed since the onset of symptoms Thrombolytic therapy or Thrombectomy Intracranial hemorrhage Vascular malformations The presence of contraindications to Aspirin, Clopidogrel or Ticagrelor Severe or moderate Ischemic Stroke (NIHSS>>12) Lack of patient consent to enter the study The presence of acute coronary syndrome at the beginning of hospitalization cardioembolic Stroke or TIA I63 Cerebral infarction Prevention Intervention group: (Ticagrelor/Aspirin): Aspirin (a loading dose of 100-300 mg as one to three tablets of 100 mg on the first day and then 80 mg once a day) together with Ticagrelor (loading dose of 180 mg ) is prescribed as two tablets of 90 mg on day 1 and then 90 mg twice a day until day 30. Recurrence of stroke. Timepoint: 21 days, 3 months, 6 months from the beginning of the study. Method of measurement: Clinical history and in case of recurrence of stroke symptoms, imaging findings. Intracranial hemorrhage, Dyspnea, Mortality. Timepoint: 21 days, 3 months, 6 months from the beginning of the study. Method of measurement: Clinical history and Imaging findings in case of Symptoms related to Intracranial hemorrhage or Dyspnea. Ahvaz University of Medical Sciences Approved 2024-01-13 Reserch Ethics Committees of Ahvaz Jundishapur of University of Medical Sciences Ahvaz, Golestan region, Farvardin Street, Golestan Hospital, Department of Neurology Ahvaz Khouzestan Iran (Islamic Republic of)