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IRCT20200501047254N3 IRCT 2024-03-02 Gonabad University of Medical Sciences Effect of Propofol Drug on Lipid Level and Blood PH Examining the effect of using the drug propofol in anesthesia on the blood fat and bicarbonate ion levels in patients undergoing spinal surgery 2024-02-20 anticipated 58 Complete https://irct.ir/trial/75355 interventional Randomization: N/A, Blinding: Single blinded, Placebo: Not used, Assignment: Other, Purpose: Treatment, Blinding description: Blinding is done in one blind way so that the study data is collected in two groups A and B by the researcher and during the analysis, the person analyzing will not know how the data is allocated in the two groups. 2-3 Spine surgery. Intervention group: This group will include patients who are candidates for spine surgery under anesthesia with propofol at a dose of 10 mg/kg/hour Product of B-Broun, Germany that they have been under anesthesia with propofol for at least 4 hours.. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Due to the project not being completed and the results of the research not being determined, there is still no plan to publish the data.
public Mohammad Taghi Khodadadi
Nurse Blvd., Saadi St., Allameh Bahloul Gonabadi Hospital
Gonabad Iran (Islamic Republic of) 9691793718 +98 51 5723 6833 dr_khodadadi_m@yahoo.com Gonabad University of Medical Sciences scientific Mohammad Taghi Khodadadi
Nurse Blvd., Saadi St., Allameh Bahloul Gonabadi Hospital
Gonabad Iran (Islamic Republic of) 9691793718 +98 51 5723 6833 dr_khodadadi_m@yahoo.com Gonabad University of Medical Sciences Iran (Islamic Republic of) Informed consent of the patient to participate in the research Patient age between 20 and 70 years Patient with ASA class I and II Duration of surgery at least 4 hours Blood fat before the operation should be at a normal level (less than 200). Blood pH should be at a normal level before the operation. Do not have underlying diseases including liver and blood diseases. The patient should not be a candidate for surgery due to trauma and in emergency conditions. The patient does not have a history of drug addiction. The patient should not be overweight or obese. The patient does not have a history of taking antipsychotic drugs 20 years 70 years Both Patient withdrawal from participating in research Occurrence of heart and respiratory problems before the start of the plan Treatment - Drugs Intervention group: This group will include patients who are candidates for spine surgery under anesthesia with propofol at a dose of 10 mg/kg/hour Product of B-Broun, Germany that they have been under anesthesia with propofol for at least 4 hours. Blood triglyceride levels. Timepoint: Before starting NPO, 4 hours after surgery. Method of measurement: Triglyceride test product of Dialab company. Blood PH level. Timepoint: Before starting fasting, 4 hours after surgery. Method of measurement: ABG Test. Blood bicarbonate ion level. Timepoint: Before starting fasting, 4 hours after surgery. Method of measurement: ABG Test. HDL Level. Timepoint: Before starting NPO, 4 hours after surgery. Method of measurement: HDL test product of Dialab company. LDL Level. Timepoint: Before starting NPO, 4 hours after surgery. Method of measurement: LDL test product of Bionic company. Cholesterol Level. Timepoint: Before starting NPO, 4 hours after surgery. Method of measurement: Cholesterol test product of Dialab company. Gonabad University of Medical Sciences Approved 2024-02-07 Ethics Committee of Gonabad University of Medical Sciences Ghadir Square, Imam Khomeini Street, Gonabad Medical Sciences Headquarters Gonabad Razavi Khorasan Iran (Islamic Republic of)