IRCT20240208060941N1 IRCT 2024-02-14 Pak Emirates Military Hospital Comparison between Pregabalin and Sertraline for treatment of itching in kidney failure Comparison between Pregabalin and Sertraline for treatment of Uremic Pruritus 2023-10-01 anticipated 46 Complete https://irct.ir/trial/75423 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization was done using computer generated sequences, prepared online, Blinding description: The 5-D itch Scale questionnaire would be self-administered, but the first author of this study would be available to answer patients’ queries and to ensure that there was is missing data on these forms. He would remain blinded to treatment being given. N/A end stage renal disease. Intervention 1: Intervention group 1: Pregabalin group. Intervention 2: Intervention group 2: Sertraline group. Yes - There is a plan to make this available What will be shared: The Deidentified Individual Participant Data Set, Study Protocol, Statistical Analysis Plan, and Informed Consent forms will be made available to desirous researchers upon reasonable requests, and after clearance from the institutional data registry body. The said documents will be shared in a non-editable format via email after scrutinizing the need for subject documents by the requesting authorities. When: The above-mentioned documents will be available after December 2024 for 10 years as per institutional data registry protocols. To whom: The data will be available only for non-commercial research purposes and will be provided to academic institutions only. Conditions: The data/ document can be used for literary and non-commercial purposes. Where to obtain: The Data can be obtained via email from: Dr Muhammad Iqbal Department of Medicine, Pak Emirates Military Hospital, Abid Majeed Road, Rawalpindi, Punjab, Pakistan, 46000. Email: iqbalkharal2934@gmail.com How to obtain: Data requests can be directly made to Dr Muhammad Iqbal via email provided earlier. After the request is received, it will submitted to the Institutional Data Control and Registry Committee for necessary verification and clearance of the requested documents. Any additional information required by the committee will be forwarded to the requestee via email. After satisfying requirements of the Institutional Data Control and Registry Committee, the requested data/ documents will shared with the requesting person via suitable means. This process may take up to 6 weeks from the date of reception of the request. Comments: