]>
IRCT20240312061271N1 IRCT 2024-04-02 Semnan University of Medical Sciences comparative effects of bilateral and unilateral transcranial direct current stimulation (tDCS) over the motor cortex on motor learning in healthy older adults comparative effects of bilateral and unilateral transcranial direct current stimulation (tDCS) over the motor cortex on motor learning in healthy older adults 2024-04-20 anticipated 54 Complete https://irct.ir/trial/75987 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: For this study, a simple and easily accessible sampling method will be used. Individuals will be divided into three groups completely at random. To ensure randomization, the block method will be used along with random tables to select numbers between 1 and 6. A treatment allocation list will then be created based on each number. Boxes will be numbered in a random sequence and each box will contain either the desired intervention or a sheet with random allocation written on it. These boxes will be completely sealed and given to the administrator and researcher based on the order of arrival of the patients. Using the aforementioned items, the standard intervention and treatment group for each person will be determined, Blinding description: To minimize bias in the study, all treatment steps will be performed by the main researcher, while the evaluation steps before and after the intervention will be carried out by a research assistant who is a physiotherapist. Participants in each group will not be informed about the treatment of the other group, and the evaluator will not be aware of which group each participant belongs to. N/A Motor learning of the healthy young elderly. Intervention 1: The first intervention group: receiving unilateral anodal tDCS. The active anode electrode is placed on the left M1 area of the brain (C3) and the cathode electrode is placed on the right side of the forehead area for 20 minutes with an intensity of 1 mA. Intervention 2: The second intervention group: received bilateral tDCS. The anode electrode is placed on the left M1 area, and the cathode electrode is placed on the right M1 area for 20 minutes with an intensity of 1 mA. Intervention 3: Control group: will receive a simulated electrical stimulation of the motor area of the brain, known as sham tDCS. The placement of the electrodes will be chosen randomly. The current will increase for the first 45 seconds and then remain constant for 60 seconds, before being turned off completely. Similar to the other groups, the electrodes will remain inactive for up to 20 minutes after the procedure. No - There is not a plan to make this available Justification or reason for not sharing IPD is No additional information available
public Yaghoubali Shourvarzi
No. 1, Sub-section 17, Quds St.
Semnan Iran (Islamic Republic of) 3515771979 +98 51 4225 7369 shourvarziy@gmail.com Semnan University of Medical Sciences scientific Fatemeh Ehsani
Neuromuscular Rehabilitation Research Center, Tabatabai Clinic, Quds Boulevard, Mashahir Square
Semnan Iran (Islamic Republic of) 3519618375 +98 23 3332 8502 fatemehehsani59@yahoo.com Semnan University of Medical Sciences Iran (Islamic Republic of) Healthy young elderly people with an age range of 60-75 years. The dominant hand of the participants should be the right hand. Willingness to participate in the study and sign the informed consent form. 60 years 75 years Both Reporting any history of neurological diseases such as Parkinson's, Alzheimer's, schizophrenia and dyslexia in such a way that the disease has affected the person's ability to learn. Report any history of psychological illness Report exposure to currents affecting the central nervous system during the last two weeks Report on the use of any type of sedative medication during the last two days Report any symptoms of forgetfulness and depression Memory disorders with a score of less than 21 through the MMSE test The presence of any symptoms of movement disorders in the upper limb of the right hand, which, according to the researcher's evaluation and diagnosis, has caused movement restrictions in the joints of the upper limb. Observing any symptoms of radiculopathy and carpal tunnel syndrome in the right hand with the researcher's diagnosis Report uncorrected vision and hearing impairments Report dizziness Pacemaker users Contraindications to the use of electrical stimulation Inability to understand or follow the study process Reluctance to participate in the study Treatment - Devices Treatment - Devices Placebo The first intervention group: receiving unilateral anodal tDCS. The active anode electrode is placed on the left M1 area of the brain (C3) and the cathode electrode is placed on the right side of the forehead area for 20 minutes with an intensity of 1 mA. The second intervention group: received bilateral tDCS. The anode electrode is placed on the left M1 area, and the cathode electrode is placed on the right M1 area for 20 minutes with an intensity of 1 mA. Control group: will receive a simulated electrical stimulation of the motor area of the brain, known as sham tDCS. The placement of the electrodes will be chosen randomly. The current will increase for the first 45 seconds and then remain constant for 60 seconds, before being turned off completely. Similar to the other groups, the electrodes will remain inactive for up to 20 minutes after the procedure. Number of errors. Timepoint: Before, immediately after, and 72 hours post tDCS application. Method of measurement: Color matching test software. Reaction time. Timepoint: Before, immediately after, and 72 hours post tDCS application. Method of measurement: Color matching test software. Semnan University of Medical Sciences Approved 2024-03-12 Ethics Committee of Semnan University of Medical Sciences Semnan University of Medical Sciences and Health Services Headquarters, Basij Blvd, Semnan Semnan Semnan Iran (Islamic Republic of)